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Expression of the endogenous and heterologous clavulanic acid cluster in Streptomyces flavogriseus: why a silent cluster is sleeping
by
Álvarez Álvarez, Rubén
, Fernández Braña, Alfredo Javier
, Pérez Redondo, R
, Martín, Juan F
, Martínez Burgo, Yolanda
, Liras, Paloma
in
Acid production
/ Acids
/ Analysis
/ Applied Genetics and Molecular Biotechnology
/ Bacteria
/ Bioassays
/ Biology
/ Biomedical and Life Sciences
/ Biosynthesis
/ Biosynthetic Pathways
/ Biosynthetic Pathways - genetics
/ Biotechnology
/ Chromatography
/ clavulanic acid
/ Clavulanic Acid - metabolism
/ Enzymes
/ Gene expression
/ Gene Expression Profiling
/ Gene Expression Regulation, Bacterial
/ Genes
/ genetic background
/ genetics
/ Genomes
/ high performance liquid chromatography
/ host strains
/ Life Sciences
/ Liquid chromatography
/ metabolism
/ Metabolites
/ Microbial Genetics and Genomics
/ Microbiology
/ Multigene Family
/ Physiological aspects
/ Real-Time Polymerase Chain Reaction
/ regulator genes
/ Reverse Transcriptase Polymerase Chain Reaction
/ Saccharomonospora viridis
/ Streptomyces
/ Streptomyces - genetics
/ Streptomyces - metabolism
/ Streptomyces clavuligerus
/ Streptomyces flavogriseus
/ Studies
2013
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Expression of the endogenous and heterologous clavulanic acid cluster in Streptomyces flavogriseus: why a silent cluster is sleeping
by
Álvarez Álvarez, Rubén
, Fernández Braña, Alfredo Javier
, Pérez Redondo, R
, Martín, Juan F
, Martínez Burgo, Yolanda
, Liras, Paloma
in
Acid production
/ Acids
/ Analysis
/ Applied Genetics and Molecular Biotechnology
/ Bacteria
/ Bioassays
/ Biology
/ Biomedical and Life Sciences
/ Biosynthesis
/ Biosynthetic Pathways
/ Biosynthetic Pathways - genetics
/ Biotechnology
/ Chromatography
/ clavulanic acid
/ Clavulanic Acid - metabolism
/ Enzymes
/ Gene expression
/ Gene Expression Profiling
/ Gene Expression Regulation, Bacterial
/ Genes
/ genetic background
/ genetics
/ Genomes
/ high performance liquid chromatography
/ host strains
/ Life Sciences
/ Liquid chromatography
/ metabolism
/ Metabolites
/ Microbial Genetics and Genomics
/ Microbiology
/ Multigene Family
/ Physiological aspects
/ Real-Time Polymerase Chain Reaction
/ regulator genes
/ Reverse Transcriptase Polymerase Chain Reaction
/ Saccharomonospora viridis
/ Streptomyces
/ Streptomyces - genetics
/ Streptomyces - metabolism
/ Streptomyces clavuligerus
/ Streptomyces flavogriseus
/ Studies
2013
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Expression of the endogenous and heterologous clavulanic acid cluster in Streptomyces flavogriseus: why a silent cluster is sleeping
by
Álvarez Álvarez, Rubén
, Fernández Braña, Alfredo Javier
, Pérez Redondo, R
, Martín, Juan F
, Martínez Burgo, Yolanda
, Liras, Paloma
in
Acid production
/ Acids
/ Analysis
/ Applied Genetics and Molecular Biotechnology
/ Bacteria
/ Bioassays
/ Biology
/ Biomedical and Life Sciences
/ Biosynthesis
/ Biosynthetic Pathways
/ Biosynthetic Pathways - genetics
/ Biotechnology
/ Chromatography
/ clavulanic acid
/ Clavulanic Acid - metabolism
/ Enzymes
/ Gene expression
/ Gene Expression Profiling
/ Gene Expression Regulation, Bacterial
/ Genes
/ genetic background
/ genetics
/ Genomes
/ high performance liquid chromatography
/ host strains
/ Life Sciences
/ Liquid chromatography
/ metabolism
/ Metabolites
/ Microbial Genetics and Genomics
/ Microbiology
/ Multigene Family
/ Physiological aspects
/ Real-Time Polymerase Chain Reaction
/ regulator genes
/ Reverse Transcriptase Polymerase Chain Reaction
/ Saccharomonospora viridis
/ Streptomyces
/ Streptomyces - genetics
/ Streptomyces - metabolism
/ Streptomyces clavuligerus
/ Streptomyces flavogriseus
/ Studies
2013
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Expression of the endogenous and heterologous clavulanic acid cluster in Streptomyces flavogriseus: why a silent cluster is sleeping
Journal Article
Expression of the endogenous and heterologous clavulanic acid cluster in Streptomyces flavogriseus: why a silent cluster is sleeping
2013
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Overview
This work was supported by grants BIO2009-09820 and LE046A11-2 from the Spanish Ministry of Economy and Competitivity and the Junta de Castilla y León, respectively. R. Álvarez-Álvarez and Y. Martínez-Burgo received PFU fellowships from the Spanish Ministry of Education, Culture and Sports. We appreciate the collaboration of Dr. T. López-García in the design of oligonucleotides and RT-qPCR experiments and the reception of plasmid pFL1272 from Dr. F. Lombo.
Publisher
Springer Berlin Heidelberg,Springer,Springer Nature B.V
Subject
/ Acids
/ Analysis
/ Applied Genetics and Molecular Biotechnology
/ Bacteria
/ Biology
/ Biomedical and Life Sciences
/ Biosynthetic Pathways - genetics
/ Clavulanic Acid - metabolism
/ Enzymes
/ Gene Expression Regulation, Bacterial
/ Genes
/ genetics
/ Genomes
/ high performance liquid chromatography
/ Microbial Genetics and Genomics
/ Real-Time Polymerase Chain Reaction
/ Reverse Transcriptase Polymerase Chain Reaction
/ Studies
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