Journal Article

Femtosecond laser enabled keratoplasty for advanced keratoconus

Shivanna, Yathish, Kugar, Thungappa, Shetty, Rohit, Nagaraja, Harsha

2013

Overview

Purpose : To assess the efficacy and advantages of femtosecond laser enabled keratoplasty (FLEK) over conventional penetrating keratoplasty (PKP) in advanced keratoconus. Materials and Methods: Detailed review of literature of published randomized controlled trials of operative techniques in PKP and FLEK. Results: Fifteen studies were identified, analyzed, and compared with our outcome. FLEK was found to have better outcome in view of better and earlier stabilization uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), and better refractive outcomes with low astigmatism as compared with conventional PKP. Wound healing also was noticed to be earlier, enabling early suture removal in FLEK. Conclusions: Studies relating to FLEK have shown better results than conventional PKP, however further studies are needed to assess the safety and intraoperative complications of the procedure.

• Publisher: Medknow Publications,Medknow Publications and Media Pvt. Ltd,Medknow Publications & Media Pvt. Ltd,Medknow Publications & Media Pvt Ltd,Wolters Kluwer Medknow Publications
• Subject: acanth / Accelerated corneal cross linking / Acute corneal hydrops / Care and treatment / Collagen cross linking / Contact lens / Cornea / Cornea collagen cross linking / Corneal collagen cross linking / Corneal cross-linking / Corneal cross-linking techniques / corneal ectasia / corneal ectosia / corneal edema / corneal laser surgery / Corneal Surgery, Laser - methods / Corneal topography / corneal transplant / crosslinking / Deep anterior lamellar keratoplasty / Deregulation / Disease pathogenesis / ectasia / Ectatic disease / Epidemiology / Femtosecond enabled keratoplasty / fungus / gene expression / genetic heterogeneity / genetics and genomics / genome-wide association study / genomic loci / Humans / hypoosmolar riboflavin / imaging / Implantable collamer lens / intra corneal ring implants / Intrastromal corneal rings segments / keratoconous / Keratoconus / Keratoconus - surgery / lamellar keratoplasty / Laser in situ keratomileusis surgery / Laser therapy / Lasers / Lasers, Excimer - therapeutic use / LASIK ectosia prophylaxis / linkage mapping / long term results / mass spectroscopy / microbial keratitis / modulus / molecular mechanisms / new technologies / ocular allergy / optical coherence tomography / Patient outcomes / Patients / pediatric keratoconus / penetrating keratoplasty / piggy back contact lenses / placido disc based topography / prevalence / proteomics / radiant exposure / riboflavin / rigid gas permeable / scheimpflug imaging / scleral lens / signaling pathways / Surgery / Symposium: Keratoconus / SynergEyes / thin cornea / topography-guided custom ablation treatment / toric implantable collamer lens / toric soft contact lens / transepithelial collagen cross-linking / Transplantation / Transplants & implants / treatment / Treatment Outcome / ultraviolet-A / UV light / vernal keratoconjunctivitis / very high fluence collagen cross-linking / Visual Acuity - physiology / whole exome-genome sequencing / Wound healing