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Clinical trial registration and results reporting: a call for transparency, coordination, and meaningful enforcement
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Clinical trial registration and results reporting: a call for transparency, coordination, and meaningful enforcement
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Clinical trial registration and results reporting: a call for transparency, coordination, and meaningful enforcement
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Journal Article
Clinical trial registration and results reporting: a call for transparency, coordination, and meaningful enforcement
2024
Overview
Trial registration and timely reporting are critical safeguards against data manipulation, cherry-picking of results, and persisting biases in favor of publishing only positive findings. Withholding clinical trial findings is not only wasteful of research resources, but also leads to the risk of misinformed clinical decisions and dishonors the contributions of participants who agreed to take part in the trials--at times at serious risks to themselves--to help generate new knowledge about an intervention's safety, effectiveness, or both. Every set of trial results that fails to see the light of day compromises trial participants' investment and trust in the knowledge generation process.
Publisher
CMA Impact Inc,CMA Impact, Inc
