Journal Article

Age-related changes in oscillatory power affect motor action

Yeldesbay, Azamat, Daun, Silvia, Popovych, Svitlana, Fink, Gereon R., Liu, Liqing, Rosjat, Nils, Grefkes, Christian B., Wang, Bin A., Toth, Tibor I., Viswanathan, Shivakumar

2017

Overview

With increasing age cognitive performance slows down. This includes cognitive processes essential for motor performance. Additionally, performance of motor tasks becomes less accurate. The objective of the present study was to identify general neural correlates underlying age-related behavioral slowing and the reduction in motor task accuracy. To this end, we continuously recorded EEG activity from 18 younger and 24 older right-handed healthy participants while they were performing a simple finger tapping task. We analyzed the EEG records with respect to local changes in amplitude (power spectrum) as well as phase locking between the two age groups. We found differences between younger and older subjects in the amplitude of post-movement synchronization in the β band of the sensory-motor and medial prefrontal cortex (mPFC). This post-movement β amplitude was significantly reduced in older subjects. Moreover, it positively correlated with the accuracy with which subjects performed the motor task at the electrode FCz, which detects activity of the mPFC and the supplementary motor area. In contrast, we found no correlation between the accurate timing of local neural activity, i.e. phase locking in the δ-θ frequency band, with the reaction and movement time or the accuracy with which the motor task was performed. Our results show that only post-movement β amplitude and not δ-θ phase locking is involved in the control of movement accuracy. The decreased post-movement β amplitude in the mPFC of older subjects hints at an impaired deactivation of this area, which may affect the cognitive control of stimulus-induced motor tasks and thereby motor output.

• Publisher: Public Library of Science,Public Library of Science (PLoS)
• Subject: Age / Aging / Aging (Biology) / Biology and Life Sciences / Cognitive ability / Cognitive tasks / Correlation analysis / Cortex (motor) / Cortex (somatosensory) / Deactivation / EEG / Electroencephalography / Frequency dependence / Handedness / Locking / Medicine / Medicine and Health Sciences / Motor skills / Motor task performance / Neural networks / Neural oscillations / Neurology / Neurosciences / Older people / People and Places / Physiological aspects / Physiology / Prefrontal cortex / Psychological aspects / Research and Analysis Methods / Social Sciences / Somatosensory cortex / Supplementary motor area / Synchronism / Synchronization / Zoology