Asset Details
Do you wish to reserve the book?
Genital warts and infection with human immunodeficiency virus in high-risk women in Burkina Faso: a longitudinal study
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Genital warts and infection with human immunodeficiency virus in high-risk women in Burkina Faso: a longitudinal study
Do you wish to request the book?
Genital warts and infection with human immunodeficiency virus in high-risk women in Burkina Faso: a longitudinal study
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Genital warts and infection with human immunodeficiency virus in high-risk women in Burkina Faso: a longitudinal study
2011
Overview
Background
Human papillomaviruses are the most common sexually transmitted infections, and genital warts, caused by HPV-6 and 11, entail considerable morbidity and cost. The natural history of genital warts in relation to HIV-1 infection has not been described in African women. We examined risk factors for genital warts in a cohort of high-risk women in Burkina Faso, in order to further describe their epidemiology.
Methods
A prospective study of 765 high-risk women who were followed at 4-monthly intervals for 27 months in Burkina Faso. Logistic and Cox regression were used to identify factors associated with prevalent, incident and persistent genital warts, including HIV-1 serostatus, CD4+ count, and concurrent sexually transmitted infections. In a subset of 306 women, cervical HPV DNA was tested at enrolment.
Results
Genital wart prevalence at baseline was 1.6% (8/492) among HIV-uninfected and 7.0% (19/273) among HIV-1 seropositive women. Forty women (5.2%) experienced at least one incident GW episode. Incidence was 1.1 per 100 person-years among HIV-uninfected women, 7.4 per 100 person-years among HIV-1 seropositive women with a nadir CD4+ count >200 cells/μL and 14.6 per 100 person-years among HIV-1 seropositive women with a nadir CD4+ count ≤200 cells/μL. Incident genital warts were also associated with concurrent bacterial vaginosis, and genital ulceration. Antiretroviral therapy was not protective against incident or persistent genital warts. Detection of HPV-6 DNA and abnormal cervical cytology were strongly associated with incident genital warts.
Conclusions
Genital warts occur much more frequently among HIV-1 infected women in Africa, particularly among those with low CD4+ counts. Antiretroviral therapy did not reduce the incidence or persistence of genital warts in this population.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
Acquired immune deficiency syndrome
/ Adult
/ AIDS
/ Condylomata Acuminata - complications
/ Condylomata Acuminata - epidemiology
/ Condylomata Acuminata - immunology
/ Condylomata Acuminata - virology
/ Cytology
/ DNA
/ Female
/ HIV
/ HIV - isolation & purification
/ HIV Infections - complications
/ HIV Infections - epidemiology
/ Human immunodeficiency virus
/ Human immunodeficiency virus 1
/ Human papillomavirus 6 - isolation & purification
/ Human papillomavirus 6 - physiology
/ Humans
/ Medicine
/ Sexually transmitted diseases
/ STD
/ Women
