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Transient portal vein thrombosis in liver cirrhosis

by Arora, Ankur , De Stefano, Valerio , Yang, Sien-Sing , Qi, Xingshun , Tacke, Frank , Mancuso, Andrea , Valla, Dominique-Charles , Méndez-Sánchez, Nahum , Teschke, Rolf , Yoshida, Eric M. , Sugawara, Yasuhiko , Guo, Xiaozhong

in Adult / Anticoagulants / Anticoagulants (Medicine) / Anticoagulants - pharmacology / Anticoagulants - therapeutic use / Anticoagulation / Biomedicine / Bleeding / Blood clot / Blood clots / Blood pressure / Bone surgery / Care and treatment / Cirrhosis / Clinical outcomes / Complications and side effects / Dosage and administration / Drug therapy / Esophagus / Female / Health aspects / Humans / Liver / Liver cirrhosis / Liver Cirrhosis - complications / Liver Cirrhosis - pathology / Male / Managing liver disease / Medicine / Medicine & Public Health / Minireview / Patients / Portal vein / Portal Vein - abnormalities / Portal vein thrombosis / Prognosis / Recanalization / Risk factors / Thromboembolism / Thrombosis / Tomography / Transient / Treatment Outcome / Veins & arteries / Venous Thrombosis - etiology / Venous Thrombosis - mortality / Venous Thrombosis - pathology

2018

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Transient portal vein thrombosis in liver cirrhosis

2018

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Transient portal vein thrombosis in liver cirrhosis

2018

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Journal Article

Transient portal vein thrombosis in liver cirrhosis

Arora, Ankur,

De Stefano, Valerio,

Yang, Sien-Sing,

Qi, Xingshun,

Tacke, Frank,

Mancuso, Andrea,

Valla, Dominique-Charles,

Méndez-Sánchez, Nahum,

Teschke, Rolf,

Yoshida, Eric M.,

Sugawara, Yasuhiko,

Guo, Xiaozhong

2018

Overview

In real-world clinical practice, the acceptance of anticoagulation therapy in the management of portal vein thrombosis (PVT) in patients with cirrhosis is limited by the fear of an increased bleeding risk. Additionally, accumulating evidence indicates that spontaneous recanalization of PVT may occur in the absence of antithrombotic treatment. Therefore, risk stratification based on outcomes in such patients is crucial for determining a therapeutic strategy. In this paper, we draw attention to the distinct clinical entity, “transient PVT” by introducing two cases with PVT that spontaneously recanalized in the absence of antithrombotic treatment. We reviewed the available data regarding the probability of and predictors for spontaneous recanalization of PVT. Available data suggest singling out transient thrombosis in the natural history of PVT in patients with cirrhosis because of its prognostic and management implications.

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Publisher

BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC

Subject

Adult

/ Anticoagulants

/ Anticoagulants (Medicine)

/ Anticoagulants - pharmacology

/ Anticoagulants - therapeutic use

/ Anticoagulation

/ Biomedicine