Asset Details
Do you wish to reserve the book?
Effect of Human Rotavirus Vaccine on Severe Diarrhea in African Infants
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Effect of Human Rotavirus Vaccine on Severe Diarrhea in African Infants
Do you wish to request the book?
Effect of Human Rotavirus Vaccine on Severe Diarrhea in African Infants
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Effect of Human Rotavirus Vaccine on Severe Diarrhea in African Infants
2010
Overview
Rotavirus is the leading cause of gastroenteritis in children worldwide. In this report, the efficacy of the rotavirus vaccine among 4417 children in Malawi and South Africa was studied in a randomized trial. Severe rotavirus gastroenteritis occurred in 4.9% of the infants in the placebo group as compared with 1.9% of the infants in the pooled vaccine group; the vaccine efficacy was 61.2%.
In this trial of rotavirus vaccine in Malawi and South Africa, severe rotavirus gastroenteritis occurred in 4.9% of the infants in the placebo group as compared with 1.9% of the infants in the pooled vaccine group; the vaccine efficacy was 61.2%.
Rotavirus is the most important cause of severe gastroenteritis among children worldwide. The World Health Organization (WHO) estimates that globally 527,000 deaths occur each year among children as a result of rotavirus infection
1
; more than 230,000 of the deaths occur in sub-Saharan Africa. Six of the seven countries with the highest mortality due to rotavirus diarrhea are located in Africa.
2
Similarly, data generated from global rotavirus surveillance networks highlight the burden of hospitalizations for rotavirus
3
; among young children hospitalized for acute diarrhea, the median detection rate for rotavirus was 40% globally and 41% in Africa. Therefore, measures to . . .
Publisher
Massachusetts Medical Society
Subject
/ Biological and medical sciences
/ Children
/ Clinics
/ Consent
/ Diarrhea
/ Diarrhea, Infantile - epidemiology
/ Diarrhea, Infantile - prevention & control
/ Female
/ Gastroenteritis - epidemiology
/ Gastroenteritis - prevention & control
/ HIV
/ Human immunodeficiency virus
/ Humans
/ Infant
/ Infants
/ Male
/ Rotavirus - isolation & purification
/ Rotavirus Infections - epidemiology
/ Rotavirus Infections - immunology
/ Rotavirus Infections - prevention & control
/ Rotavirus Vaccines - administration & dosage
/ Rotavirus Vaccines - adverse effects
/ Rotavirus Vaccines - immunology
/ Teams
/ Vaccines
/ Vaccines, Attenuated - administration & dosage
/ Vaccines, Attenuated - adverse effects
/ Vaccines, Attenuated - immunology
/ Viruses
