Journal Article

Automatic application of neural stimulation during wheelchair propulsion after SCI enhances recovery of upright sitting from destabilizing events

Lombardo, Lisa M., Armstrong, Kiley L., Foglyano, Kevin M., Triolo, Ronald J., Audu, Musa L.

2018

Overview

Background The leading cause of injury for manual wheelchair users are tips and falls caused by unexpected destabilizing events encountered during everyday activities. The purpose of this study was to determine the feasibility of automatically restoring seated stability to manual wheelchair users with spinal cord injury (SCI) via a threshold-based system to activate the hip and trunk muscles with electrical stimulation during potentially destabilizing events. Methods We detected and classified potentially destabilizing sudden stops and turns with a wheelchair-mounted wireless inertial measurement unit (IMU), and then applied neural stimulation to activate the appropriate muscles to resist trunk movement and restore seated stability. After modeling and preliminary testing to determine the appropriate inertial signatures to discriminate between events and reliably trigger stimulation, the system was implemented and evaluated in real-time on manual wheelchair users with SCI. Three participants completed simulated collision events and four participants completed simulated rapid turns. Data were analyzed as a series of individual case studies with subjects acting as their own controls with and without the system active. Results The controller achieved 93% accuracy in detecting collisions and right turns, and 100% accuracy in left turn detection. Two of the three subjects who participated in collision testing with stimulation experienced significantly decreased maximum anterior-posterior trunk angles ( p  < 0.05). Similar results were obtained with implanted and surface stimulation systems. Conclusions This study demonstrates the feasibility of a neural stimulation control system based on simple inertial measurements to improve trunk stability and overall safety of people with spinal cord injuries during manual wheelchair propulsion. Further studies are required to determine clinical utility in real world situations and generalizability to the broader SCI or other population of manual or powered wheelchair users. Trial registration ClinicalTrials.gov Identifier NCT01474148 . Registered 11/08/2011 retrospectively registered. 

• Publisher: BioMed Central,BioMed Central Ltd,BMC
• Subject: Accidental Falls - prevention & control / Adult / Analysis / Biomechanical Phenomena / Biomedical and Life Sciences / Biomedical Engineering and Bioengineering / Biomedicine / Care and treatment / Electric Stimulation Therapy - methods / Equipment Design - methods / Event detection / Female / Functional neuromuscular stimulation / Humans / Male / Middle Aged / Neural stimulation / Neurology / Neurosciences / Persons with Disabilities / Postural Balance - physiology / Prognosis / Rehabilitation Medicine / Retrospective Studies / Risk factors / Sitting Position / Spinal Cord Injuries / Spinal cord injury / Thrombosis / Wheelchairs / Wheelchairs - adverse effects