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The effects of plasma chromium on lipid profile, glucose metabolism and cardiovascular risk in type 2 diabetes mellitus. A case - control study
by
Ngala, Robert Amadu
, Nsiah, Paul
, Awe, Martin Akilla
in
Adult
/ Analysis
/ Atherosclerosis
/ Atomic absorption analysis
/ Atomic properties
/ Biology and Life Sciences
/ Blood
/ Blood & organ donations
/ Blood Glucose
/ Blood pressure
/ C-Reactive Protein
/ Cardiovascular diseases
/ Cardiovascular Diseases - blood
/ Cardiovascular Diseases - complications
/ Cardiovascular Diseases - pathology
/ Chromium
/ Chromium - blood
/ Diabetes
/ Diabetes mellitus
/ Diabetes mellitus (non-insulin dependent)
/ Diabetes Mellitus, Type 2 - blood
/ Diabetes Mellitus, Type 2 - complications
/ Diabetes Mellitus, Type 2 - pathology
/ Enzyme-linked immunosorbent assay
/ Fasting
/ Female
/ Glucose
/ Glucose metabolism
/ Health aspects
/ Health risks
/ Humans
/ Hyperglycemia
/ Hyperinsulinemia
/ Hypertension
/ Immunoassay
/ Insulin
/ Insulin - blood
/ Insulin resistance
/ Insulin Resistance - physiology
/ Laboratories
/ Lipid metabolism
/ Lipids
/ Lipids - blood
/ Lipoproteins
/ Lipoproteins (very low density)
/ Lipoproteins test
/ Lipoproteins, LDL - blood
/ Lipoproteins, VLDL - blood
/ Low density lipoprotein
/ Male
/ Medicine and Health Sciences
/ Metabolism
/ Middle Aged
/ Minerals (Nutrients)
/ Nutrition research
/ Obesity
/ Obesity - blood
/ Obesity - complications
/ Obesity - pathology
/ Organic chemistry
/ Physical Sciences
/ Proteins
/ Random access
/ Risk Factors
/ Spectral analysis
/ Studies
/ Type 2 diabetes
/ Variables
2018
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The effects of plasma chromium on lipid profile, glucose metabolism and cardiovascular risk in type 2 diabetes mellitus. A case - control study
by
Ngala, Robert Amadu
, Nsiah, Paul
, Awe, Martin Akilla
in
Adult
/ Analysis
/ Atherosclerosis
/ Atomic absorption analysis
/ Atomic properties
/ Biology and Life Sciences
/ Blood
/ Blood & organ donations
/ Blood Glucose
/ Blood pressure
/ C-Reactive Protein
/ Cardiovascular diseases
/ Cardiovascular Diseases - blood
/ Cardiovascular Diseases - complications
/ Cardiovascular Diseases - pathology
/ Chromium
/ Chromium - blood
/ Diabetes
/ Diabetes mellitus
/ Diabetes mellitus (non-insulin dependent)
/ Diabetes Mellitus, Type 2 - blood
/ Diabetes Mellitus, Type 2 - complications
/ Diabetes Mellitus, Type 2 - pathology
/ Enzyme-linked immunosorbent assay
/ Fasting
/ Female
/ Glucose
/ Glucose metabolism
/ Health aspects
/ Health risks
/ Humans
/ Hyperglycemia
/ Hyperinsulinemia
/ Hypertension
/ Immunoassay
/ Insulin
/ Insulin - blood
/ Insulin resistance
/ Insulin Resistance - physiology
/ Laboratories
/ Lipid metabolism
/ Lipids
/ Lipids - blood
/ Lipoproteins
/ Lipoproteins (very low density)
/ Lipoproteins test
/ Lipoproteins, LDL - blood
/ Lipoproteins, VLDL - blood
/ Low density lipoprotein
/ Male
/ Medicine and Health Sciences
/ Metabolism
/ Middle Aged
/ Minerals (Nutrients)
/ Nutrition research
/ Obesity
/ Obesity - blood
/ Obesity - complications
/ Obesity - pathology
/ Organic chemistry
/ Physical Sciences
/ Proteins
/ Random access
/ Risk Factors
/ Spectral analysis
/ Studies
/ Type 2 diabetes
/ Variables
2018
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The effects of plasma chromium on lipid profile, glucose metabolism and cardiovascular risk in type 2 diabetes mellitus. A case - control study
by
Ngala, Robert Amadu
, Nsiah, Paul
, Awe, Martin Akilla
in
Adult
/ Analysis
/ Atherosclerosis
/ Atomic absorption analysis
/ Atomic properties
/ Biology and Life Sciences
/ Blood
/ Blood & organ donations
/ Blood Glucose
/ Blood pressure
/ C-Reactive Protein
/ Cardiovascular diseases
/ Cardiovascular Diseases - blood
/ Cardiovascular Diseases - complications
/ Cardiovascular Diseases - pathology
/ Chromium
/ Chromium - blood
/ Diabetes
/ Diabetes mellitus
/ Diabetes mellitus (non-insulin dependent)
/ Diabetes Mellitus, Type 2 - blood
/ Diabetes Mellitus, Type 2 - complications
/ Diabetes Mellitus, Type 2 - pathology
/ Enzyme-linked immunosorbent assay
/ Fasting
/ Female
/ Glucose
/ Glucose metabolism
/ Health aspects
/ Health risks
/ Humans
/ Hyperglycemia
/ Hyperinsulinemia
/ Hypertension
/ Immunoassay
/ Insulin
/ Insulin - blood
/ Insulin resistance
/ Insulin Resistance - physiology
/ Laboratories
/ Lipid metabolism
/ Lipids
/ Lipids - blood
/ Lipoproteins
/ Lipoproteins (very low density)
/ Lipoproteins test
/ Lipoproteins, LDL - blood
/ Lipoproteins, VLDL - blood
/ Low density lipoprotein
/ Male
/ Medicine and Health Sciences
/ Metabolism
/ Middle Aged
/ Minerals (Nutrients)
/ Nutrition research
/ Obesity
/ Obesity - blood
/ Obesity - complications
/ Obesity - pathology
/ Organic chemistry
/ Physical Sciences
/ Proteins
/ Random access
/ Risk Factors
/ Spectral analysis
/ Studies
/ Type 2 diabetes
/ Variables
2018
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The effects of plasma chromium on lipid profile, glucose metabolism and cardiovascular risk in type 2 diabetes mellitus. A case - control study
Journal Article
The effects of plasma chromium on lipid profile, glucose metabolism and cardiovascular risk in type 2 diabetes mellitus. A case - control study
2018
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Overview
The study was aimed at determining the effect of plasma chromium concentration on the metabolism of glucose, and lipids and their subsequent cardiovascular risk in patients with type 2 diabetes in the Bolgatanga district of Ghana.
Fasting blood glucose and lipids profile were determined by enzymatic assay using the BT 5000® Random Access Chemistry Analyzer. Fasting serum insulin and High sensitive C-reactive protein were determined by ELISA, a solid phase direct sandwich immunoassay method. HOMA-IR, which is based on fasting blood sample for insulin and glucose concentrations measured in a single blood sample, was used to calculate insulin resistance. Plasma chromium was measured using an atomic Absorption Spectrometer.
Patientswith diabeteshad significantly (p<0.0001) increased LDL, TC, TG, VLDL, insulin, CRP and HOMAIR and a significantly reduced plasma chromium (p<0.0001) (0.53± 0.02μg/l and 0.11±0.01μg/l control and case respectively). Low Cr (p ≤0.001) was associated with high blood pressure, obesity and lipid dysregulation. Plasma Cr significantly correlated negatively with blood pressure and LDL.
Lower plasma Cr level was associated with hyperglycaemia, hyperinsulinemia, hypertension, insulin resistance and high inflammation marker HsCRP.
Publisher
Public Library of Science,Public Library of Science (PLoS)
Subject
/ Analysis
/ Blood
/ Cardiovascular Diseases - blood
/ Cardiovascular Diseases - complications
/ Cardiovascular Diseases - pathology
/ Chromium
/ Diabetes
/ Diabetes mellitus (non-insulin dependent)
/ Diabetes Mellitus, Type 2 - blood
/ Diabetes Mellitus, Type 2 - complications
/ Diabetes Mellitus, Type 2 - pathology
/ Enzyme-linked immunosorbent assay
/ Fasting
/ Female
/ Glucose
/ Humans
/ Insulin
/ Insulin Resistance - physiology
/ Lipids
/ Lipoproteins (very low density)
/ Male
/ Medicine and Health Sciences
/ Obesity
/ Proteins
/ Studies
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