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Sinusoidal obstruction syndrome/veno-occlusive disease: current situation and perspectives—a position statement from the European Society for Blood and Marrow Transplantation (EBMT)

by Carreras, E , Savani, B N , Masszi, T , Peters, C , Dalle, J-H , Petersen, F B , Ciceri, F , Richardson, P G , Malard, F , Nagler, A , Ruutu, T , Michallet, M , Corbacioglu, S , Arat, M , Aljurf, M , Baron, F , Huynh, A , Pagluica, T , Yakoub-Agha, I , Blaise, D , Aerts, E , Fukuda, T , Alaskar, A S , Mohty, M , Wallhult, E , NiChonghaile, M , Bader, P , Abecassis, M , Duarte, R F , Bazarbachi, A

in 692/420 / 692/499 / 692/699 / 692/700/139 / Adult / Biomarkers - blood / Bone marrow / Care and treatment / Cell Biology / Complications and side effects / Diagnosis / Hematology / Hematopoietic stem cell transplantation / Hematopoietic Stem Cell Transplantation - adverse effects / Human health sciences / Humans / Hématologie / Internal Medicine / Medicine / Medicine & Public Health / Postoperative Complications - blood / Postoperative Complications - diagnosis / Postoperative Complications - physiopathology / Postoperative Complications - therapy / Prevention / Public Health / Risk Factors / Sciences de la santé humaine / Special Report / Stem cell transplantation / Stem Cells / Vascular diseases / Vascular Diseases - blood / Vascular Diseases - diagnosis / Vascular Diseases - etiology / Vascular Diseases - physiopathology / Vascular Diseases - therapy

2015

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Sinusoidal obstruction syndrome/veno-occlusive disease: current situation and perspectives—a position statement from the European Society for Blood and Marrow Transplantation (EBMT)

2015

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Sinusoidal obstruction syndrome/veno-occlusive disease: current situation and perspectives—a position statement from the European Society for Blood and Marrow Transplantation (EBMT)

2015

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Journal Article

Sinusoidal obstruction syndrome/veno-occlusive disease: current situation and perspectives—a position statement from the European Society for Blood and Marrow Transplantation (EBMT)

Carreras, E,

Savani, B N,

Masszi, T,

Peters, C,

Dalle, J-H,

Petersen, F B,

Ciceri, F,

Richardson, P G,

Malard, F,

Nagler, A,

Ruutu, T,

Michallet, M,

Corbacioglu, S,

Arat, M,

Aljurf, M,

Baron, F,

Huynh, A,

Pagluica, T,

Yakoub-Agha, I,

Blaise, D,

Aerts, E,

Fukuda, T,

Alaskar, A S,

Mohty, M,

Wallhult, E,

NiChonghaile, M,

Bader, P,

Abecassis, M,

Duarte, R F,

Bazarbachi, A

2015

Overview

Sinusoidal obstruction syndrome or veno-occlusive disease (SOS/VOD) is a potentially life-threatening complication of hematopoietic SCT (HSCT). This review aims to highlight, on behalf of the European Society for Blood and Marrow Transplantation, the current knowledge on SOS/VOD pathophysiology, risk factors, diagnosis and treatments. Our perspectives on SOS/VOD are (i) to accurately identify its risk factors; (ii) to define new criteria for its diagnosis; (iii) to search for SOS/VOD biomarkers and (iv) to propose prospective studies evaluating SOS/VOD prevention and treatment in adults and children.

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Publisher

Nature Publishing Group UK,Nature Publishing Group,Nature

Subject

692/420

/ 692/499

/ 692/699

/ 692/700/139

/ Adult

/ Biomarkers - blood

/ Bone marrow