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Artificially selecting microbial communities: If we can breed dogs, why not microbiomes?
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Artificially selecting microbial communities: If we can breed dogs, why not microbiomes?
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Journal Article
Artificially selecting microbial communities: If we can breed dogs, why not microbiomes?
2019
Overview
Natural microbial communities perform many functions that are crucial for human well-being. Yet we have very little control over them, and we do not know how to optimize their functioning. One idea is to breed microbial communities as we breed dogs: by comparing a set of microbiomes and allowing the best-performing ones to generate new communities, and so on. Although this idea seems simple, designing such a selection experiment brings with it many decisions with surprising outcomes. Xie and colleagues developed a computational model that reveals this complexity and shows how different experimental design decisions can impact the success of such an experiment.
Publisher
Public Library of Science,Public Library of Science (PLoS)
Subject
