Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

Hemagglutinin-neuraminidase and fusion proteins of virulent Newcastle disease virus cooperatively disturb fusion–fission homeostasis to enhance mitochondrial function by activating the unfolded protein response of endoplasmic reticulum and mitochondrial stress

by Yin, Yuncong , Yang, Zengqi , Rehman, Zaib Ur , Shi, Mengyu , Sun, Yingjie , Meng, Chunchun , Yang, Bin , Ding, Chan , Ren, Shanhui , Liu, Panrao , Gao, Xiaolong , Qu, Yurong

in Apoptosis / Autophagy / Avian orthoavulavirus 1 / biogenesis / Biosynthesis / Cooperation / Cytochrome / Endoplasmic reticulum / energy / enzymes / Genetic aspects / giant cells / Glycoproteins / Homeostasis / Immunology / Lectins / Life Sciences / Medicine / Medicine & Public Health / Microbiology / Mitochondria / Morphology / Newcastle disease / Pathogenic microorganisms / Plasmids / Proteins / Quality control / Short Report / Trends / unfolded protein response / Veterinary Medicine/Veterinary Science / Virology / virulence / Virulence (Microbiology) / Viruses

2019

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

by Yin, Yuncong , Yang, Zengqi , Rehman, Zaib Ur , Shi, Mengyu , Sun, Yingjie , Meng, Chunchun , Yang, Bin , Ding, Chan , Ren, Shanhui , Liu, Panrao , Gao, Xiaolong , Qu, Yurong

2019

Confirm

Do you wish to request the book?

by Yin, Yuncong , Yang, Zengqi , Rehman, Zaib Ur , Shi, Mengyu , Sun, Yingjie , Meng, Chunchun , Yang, Bin , Ding, Chan , Ren, Shanhui , Liu, Panrao , Gao, Xiaolong , Qu, Yurong

2019

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

Hemagglutinin-neuraminidase and fusion proteins of virulent Newcastle disease virus cooperatively disturb fusion–fission homeostasis to enhance mitochondrial function by activating the unfolded protein response of endoplasmic reticulum and mitochondrial stress

Yin, Yuncong,

Yang, Zengqi,

Rehman, Zaib Ur,

Shi, Mengyu,

Sun, Yingjie,

Meng, Chunchun,

Yang, Bin,

Ding, Chan,

Ren, Shanhui,

Liu, Panrao,

Gao, Xiaolong,

Qu, Yurong

2019

Overview

The fusogenically activated F and HN proteins of virulent NDV induce complete autophagic flux in DF-1 and A549 cells. However, the effect of both glycoproteins on mitochondria remains elusive. Here, we found that F and HN cooperation increases mitochondrial biogenesis but does not cause the mitochondria damage. We observed that both glycoproteins change the morphological characteristics and spatial distribution of intracellular mitochondria. F and HN cooperate cooperatively to induce ER stress and UPR mt . Our preliminary data suggested that F and HN cooperatively disturb mitochondrial fusion–fission homeostasis to enhance mitochondrial biogenesis, and eventually meet the energy demand of syncytium formation.

Share this book

Add to My Shelf

Publisher

BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC

Subject

Apoptosis

/ Autophagy

/ Avian orthoavulavirus 1