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Organ Donor Transmission of Rickettsia typhi to Kidney Transplant Recipients, Texas, USA, 2024
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Organ Donor Transmission of Rickettsia typhi to Kidney Transplant Recipients, Texas, USA, 2024
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Journal Article
Organ Donor Transmission of Rickettsia typhi to Kidney Transplant Recipients, Texas, USA, 2024
2025
Overview
Murine typhus, a fleaborne disease caused by the bacterium Rickettsia typhi, is found throughout temperate and tropical regions of the world. Transmission of R. typhi to humans involves several species of fleas, and most infections result from direct inoculation of R. typhi-infected flea feces into abrasions in the skin. We describe the transmission of R. typhi from an organ donor in Texas, USA, to 2 kidney transplant recipients. The donor and 1 recipient died from the infection. The occurrence of R. typhi transmission via transplantation is a harbinger for the reemergence of murine typhus in some of the most densely populated metropolitan areas of the United States. Our findings reinforce the need to improve healthcare provider and public awareness of this life-threatening but treatable infection.
Publisher
U.S. National Center for Infectious Diseases,Centers for Disease Control and Prevention
Subject
/ Anemia
/ Animals
/ Antigens
/ bacteria
/ Biopsy
/ Diabetes
/ Dyspnea
/ Female
/ Fever
/ Fleas
/ Humans
/ International economic relations
/ Kidney Transplantation - adverse effects
/ Kidneys
/ Male
/ Methods
/ Plasma
/ Rickettsia typhi - isolation & purification
/ to Kidney Transplant Recipients, Texas, USA, 2024
/ Typhus
/ Typhus, Endemic Flea-Borne - diagnosis
/ Typhus, Endemic Flea-Borne - epidemiology
/ Typhus, Endemic Flea-Borne - microbiology
/ Typhus, Endemic Flea-Borne - transmission
/ Urine
