Journal Article

Severe Acute Respiratory Syndrome Coronavirus 2 Prevalence, Seroprevalence, and Exposure among Evacuees from Wuhan, China, 2020

Corbett, Kizzmekia S., Steinberg, Jonathan, Mahon, Barbara, Pomeroy, Mary, Rider, Errin C., Freeman, Brandi, Odongo, George S., Carlson, Christina M., Feldstein, Leora R., Tenforde, Mark W., Stewart, Rebekah, McDonald, Emily, Bhakta, Neenaben, Thornburg, Natalie J., Saruwatari, Kim, Kamili, Shifaq, Behravesh, Casey Barton, Abedi, Glen R., Pesik, Nicki, Moser, Kathleen, Cetron, Martin, Wang, Lijuan, Lu, Xiaoyan, Abiona, Olubukola M., Douville, Gina, Lindstrom, Stephen, Borntrager, Denise, Lester, Sandra, Hallowell, Benjamin D., Hutchinson, Geoffrey B., Ishii, Kenta, Foster, Loretta, Whitaker, Brett L., Graham, Barney S., Haynes, Amber, Murray, Janna R., Killerby, Marie E., Sakthivel, Senthilkumar K., Rasheed, Mohammad, Jacobs, Jesica R., Maniatis, Panagiotis, Rotz, Lisa, Rolfes, Melissa A., Braden, Christopher, Hall, Aron J., Lynch, Brian, Malapati, Lakshmi, Brown, Clive, Roohi, Shahrokh, Knight, Nancy

2020

Overview

To determine prevalence of, seroprevalence of, and potential exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among a cohort of evacuees returning to the United States from Wuhan, China, in January 2020, we conducted a cross-sectional study of quarantined evacuees from 1 repatriation flight. Overall, 193 of 195 evacuees completed exposure surveys and submitted upper respiratory or serum specimens or both at arrival in the United States. Nearly all evacuees had taken preventive measures to limit potential exposure while in Wuhan, and none had detectable SARS-CoV-2 in upper respiratory tract specimens, suggesting the absence of asymptomatic respiratory shedding among this group at the time of testing. Evidence of antibodies to SARS-CoV-2 was detected in 1 evacuee, who reported experiencing no symptoms or high-risk exposures in the previous 2 months. These findings demonstrated that this group of evacuees posed a low risk of introducing SARS-CoV-2 to the United States.

• Publisher: U.S. National Center for Infectious Diseases,Centers for Disease Control and Prevention
• Subject: 2019 novel coronavirus disease / Adolescent / Adult / Aged / Animals / Betacoronavirus / Child / Child, Preschool / Clinical Laboratory Techniques / coronavirus disease / Coronavirus Infections - diagnosis / Coronavirus Infections - epidemiology / Coronaviruses / COVID-19 / COVID-19 Testing / Cross-Sectional Studies / Disease control / Disease transmission / Exposure / Female / Fever / Health aspects / Health care / Humans / Illnesses / Infant / Infant, Newborn / Male / Medical laboratories / Middle Aged / Pandemics / Pneumonia, Viral - epidemiology / Prevalence / Public health / Public spaces / Quarantine / Quarantine - statistics & numerical data / Repatriation / Respiratory diseases / Respiratory tract / SARS-CoV-2 / Seroepidemiologic Studies / Serology / Severe acute respiratory syndrome / Severe acute respiratory syndrome coronavirus 2 / Severe Acute Respiratory Syndrome Coronavirus 2 Prevalence, Seroprevalence, and Exposure among Evacuees from Wuhan, China, 2020 / Travel / United States - epidemiology / viruses / Young Adult