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Meta-Analysis of Laparoscopic versus Open Hepatectomy for Live Liver Donors
by
Xu, Jun
, Ye, Song
, Hu, Chen
, Cao, Hua-Li
, Zheng, Shu-Sen
, Zhang, Mang-Li
, Wang, Wei-Lin
in
Analysis
/ Bile
/ Bleeding
/ Diet
/ Dietary intake
/ Hepatectomy
/ Hepatectomy - adverse effects
/ Hepatectomy - methods
/ Hospitals
/ Humans
/ Laboratories
/ Laparoscopy
/ Laparoscopy - adverse effects
/ Laparoscopy - methods
/ Liver
/ Liver diseases
/ Liver transplantation
/ Liver Transplantation - adverse effects
/ Liver Transplantation - methods
/ Liver transplants
/ Living Donors
/ Medicine
/ Medicine and Health Sciences
/ Meta-analysis
/ Organ donors
/ Organ transplantation
/ Patient satisfaction
/ Patients
/ People and Places
/ Physical Sciences
/ Public health
/ Research and Analysis Methods
/ Studies
/ Surgery
/ Systematic review
/ Tissue donation
/ Transplantation
/ Transplants & implants
2016
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Meta-Analysis of Laparoscopic versus Open Hepatectomy for Live Liver Donors
by
Xu, Jun
, Ye, Song
, Hu, Chen
, Cao, Hua-Li
, Zheng, Shu-Sen
, Zhang, Mang-Li
, Wang, Wei-Lin
in
Analysis
/ Bile
/ Bleeding
/ Diet
/ Dietary intake
/ Hepatectomy
/ Hepatectomy - adverse effects
/ Hepatectomy - methods
/ Hospitals
/ Humans
/ Laboratories
/ Laparoscopy
/ Laparoscopy - adverse effects
/ Laparoscopy - methods
/ Liver
/ Liver diseases
/ Liver transplantation
/ Liver Transplantation - adverse effects
/ Liver Transplantation - methods
/ Liver transplants
/ Living Donors
/ Medicine
/ Medicine and Health Sciences
/ Meta-analysis
/ Organ donors
/ Organ transplantation
/ Patient satisfaction
/ Patients
/ People and Places
/ Physical Sciences
/ Public health
/ Research and Analysis Methods
/ Studies
/ Surgery
/ Systematic review
/ Tissue donation
/ Transplantation
/ Transplants & implants
2016
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Meta-Analysis of Laparoscopic versus Open Hepatectomy for Live Liver Donors
by
Xu, Jun
, Ye, Song
, Hu, Chen
, Cao, Hua-Li
, Zheng, Shu-Sen
, Zhang, Mang-Li
, Wang, Wei-Lin
in
Analysis
/ Bile
/ Bleeding
/ Diet
/ Dietary intake
/ Hepatectomy
/ Hepatectomy - adverse effects
/ Hepatectomy - methods
/ Hospitals
/ Humans
/ Laboratories
/ Laparoscopy
/ Laparoscopy - adverse effects
/ Laparoscopy - methods
/ Liver
/ Liver diseases
/ Liver transplantation
/ Liver Transplantation - adverse effects
/ Liver Transplantation - methods
/ Liver transplants
/ Living Donors
/ Medicine
/ Medicine and Health Sciences
/ Meta-analysis
/ Organ donors
/ Organ transplantation
/ Patient satisfaction
/ Patients
/ People and Places
/ Physical Sciences
/ Public health
/ Research and Analysis Methods
/ Studies
/ Surgery
/ Systematic review
/ Tissue donation
/ Transplantation
/ Transplants & implants
2016
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Meta-Analysis of Laparoscopic versus Open Hepatectomy for Live Liver Donors
Journal Article
Meta-Analysis of Laparoscopic versus Open Hepatectomy for Live Liver Donors
2016
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Overview
To document the safety and efficacy of laparoscopic living donor hepatectomy in comparison with open liver resection for living donor liver transplantation.
Medline database, EMASE and Cochrane library were searched for original studies comparing laparoscopic living donor hepatectomy (LLDH) and open living donor hepatectomy (OLDH) by January 2015. Meta-analysis was performed to evaluate donors' perioperative outcomes.
Nine studies met selection criteria, involving 1346 donors of whom 318 underwent LLDH and 1028 underwent OLDH. The Meta analysis demonstrated that LLDH group had less operative blood loss [patients 1346; WMD: -56.09 mL; 95%CI: -100.28-(-11.90) mL; P = 0.01], shorter hospital stay [patients 737; WMD: -1.75 d; 95%CI: -3.01-(-0.48) d; P = 0.007] but longer operative time (patients 1346; WMD: 41.05 min; 95%CI: 1.91-80.19 min; P = 0.04), compared with OLDH group. There were no significant difference in other outcomes between LLDH and OLDH groups, including overall complication, bile leakage, postoperative bleeding, pulmonary complication, wound complication, time to dietary intake and period of analgesic use.
LLDH appears to be a safe and effective option for LDLT. It improves donors' perioperative outcomes as compared with OLDH.
Publisher
Public Library of Science,Public Library of Science (PLoS)
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