Asset Details
Do you wish to reserve the book?
Effect of dietary nitrate on human muscle power: a systematic review and individual participant data meta-analysis
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Effect of dietary nitrate on human muscle power: a systematic review and individual participant data meta-analysis
Do you wish to request the book?
Effect of dietary nitrate on human muscle power: a systematic review and individual participant data meta-analysis
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Effect of dietary nitrate on human muscle power: a systematic review and individual participant data meta-analysis
2021
Overview
Background
Previous narrative reviews have concluded that dietary nitrate (NO
3
−
) improves maximal neuromuscular power in humans. This conclusion, however, was based on a limited number of studies, and no attempt has been made to quantify the exact magnitude of this beneficial effect. Such information would help ensure adequate statistical power in future studies and could help place the effects of dietary NO
3
−
on various aspects of exercise performance (i.e., endurance vs. strength vs. power) in better context. We therefore undertook a systematic review and individual participant data meta-analysis to quantify the effects of NO
3
−
supplementation on human muscle power.
Methods
The literature was searched using a strategy developed by a health sciences librarian. Data sources included Medline Ovid, Embase, SPORTDiscus, Scopus,
Clinicaltrials.gov
, and Google Scholar. Studies were included if they used a randomized, double-blind, placebo-controlled, crossover experimental design to measure the effects of dietary NO
3
−
on maximal power during exercise in the non-fatigued state and the within-subject correlation could be determined from data in the published manuscript or obtained from the authors.
Results
Nineteen studies of a total of 268 participants (218 men, 50 women) met the criteria for inclusion. The overall effect size (ES; Hedge’s g) calculated using a fixed effects model was 0.42 (95% confidence interval (CI) 0.29, 0.56;
p
= 6.310 × 10
− 11
). There was limited heterogeneity between studies (i.e., I
2
= 22.79%, H
2
= 1.30,
p
= 0.3460). The ES estimated using a random effects model was therefore similar (i.e., 0.45, 95% CI 0.30, 0.61;
p
= 1.064 × 10
− 9
). Sub-group analyses revealed no significant differences due to subject age, sex, or test modality (i.e., small vs. large muscle mass exercise). However, the ES in studies using an acute dose (i.e., 0.54, 95% CI 0.37, 0.71;
p
= 6.774 × 10
− 12
) was greater (
p
= 0.0211) than in studies using a multiple dose regimen (i.e., 0.22, 95% CI 0.01, 0.43;
p
= 0.003630).
Conclusions
Acute or chronic dietary NO
3
−
intake significantly increases maximal muscle power in humans. The magnitude of this effect–on average, ~ 5%–is likely to be of considerable practical and clinical importance.
Publisher
BioMed Central,BioMed Central Ltd,Taylor & Francis Ltd,Taylor & Francis Group
