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Infant Botulism, Israel, 2007–2021

by Levy, Itzhak , Straussberg, Rachel , Almagor, Yotam , Elad, Daniel , Levinsky, Yoel , Guri, Alex , Dabaja-Younis, Halima , Tasher, Diana , Goldberg, Bar , Baider, Zina , Blum, Shlomo , Danino, Dana , Scheuerman, Oded

in Age / Antibiotics / Babies / Bacteria / Births / Botulism / Botulism - diagnosis / Botulism - epidemiology / Botulism - etiology / botulism neurotoxin / Clostridium botulinum / Demographic aspects / Diagnosis / Environmental risk / Epidemiology / Food contamination / honey / Humans / Incidence / Infant / infant botulism / Infant Botulism, Israel, 2007–2021 / Infantile colic / Infants / Israel - epidemiology / Laboratory animals / Medical diagnosis / Medical prognosis / Multicenter Studies as Topic / Pediatric research / Pediatrics / Respiratory failure / Retrospective Studies / Risk factors / Statistics

2023

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Infant Botulism, Israel, 2007–2021

2023

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Infant Botulism, Israel, 2007–2021

2023

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Journal Article

Infant Botulism, Israel, 2007–2021

Levy, Itzhak,

Straussberg, Rachel,

Almagor, Yotam,

Elad, Daniel,

Levinsky, Yoel,

Guri, Alex,

Dabaja-Younis, Halima,

Tasher, Diana,

Goldberg, Bar,

Baider, Zina,

Blum, Shlomo,

Danino, Dana,

Scheuerman, Oded

2023

Overview

Infant botulism (IB) is an intestinal toxemia that manifests as descending paralysis, constipation, and, in some cases, respiratory failure. Laboratory-confirmed IB cases are rare, and recent data in Israel are lacking. We conducted a national multicenter retrospective study of laboratory-confirmed IB cases reported in Israel during 2007-2021. A total of 8 cases were reported during the study period. During 2019-2021, incidence may have increased because of a cluster of 5 cases. Infant median age for diagnosis was 6.5 months, older than previously reported (3 months). Most cases occurred during March-July. Honey consumption was reported in 1 case, and possible environmental risk factors (living nearby rural or construction areas, dust exposure, and having a father who works as a farmer) were reported in 6 cases. Although IB is rare, its incidence in Israel may have increased over recent years, and its epidemiology and risk factors differ from cases reported previously in Israel.

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Publisher

U.S. National Center for Infectious Diseases,Centers for Disease Control and Prevention

Subject

/ Babies

/ Births

/ Botulism - diagnosis