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Antigenic Characterization of Novel Human Norovirus GII.4 Variants San Francisco 2017 and Hong Kong 2019

by Kendra, Joseph A. , Niendorf, Sandra , Tohma, Kentaro , Landivar, Michael , Ford-Siltz, Lauren A. , Pilewski, Kelsey A. , Parra, Gabriel I.

in acute gastroenteritis / Antibodies, Monoclonal - immunology / Antibodies, Viral - blood / Antibodies, Viral - immunology / Antigenic Characterization of Novel Human Norovirus GII.4 Variants San Francisco 2017 and Hong Kong 2019 / Antigens, Viral - genetics / Antigens, Viral - immunology / Caliciviridae Infections - epidemiology / Caliciviridae Infections - immunology / Caliciviridae Infections - virology / Causes of / Dispatch / Distribution / Gastroenteritis / Gastroenteritis - epidemiology / Gastroenteritis - virology / Gene mutations / Genetic aspects / Genotype / GII.4 variants / Hong Kong - epidemiology / Hong Kong 2019 variant / Humans / Identification and classification / Mutation / Norovirus / Norovirus - classification / Norovirus - genetics / Norovirus - immunology / Pandemics / Phylogeny / San Francisco - epidemiology / San Francisco 2017 variant / Viral antigens / Virus research / Viruses

2024

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Antigenic Characterization of Novel Human Norovirus GII.4 Variants San Francisco 2017 and Hong Kong 2019

by Kendra, Joseph A. , Niendorf, Sandra , Tohma, Kentaro , Landivar, Michael , Ford-Siltz, Lauren A. , Pilewski, Kelsey A. , Parra, Gabriel I.

2024

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Antigenic Characterization of Novel Human Norovirus GII.4 Variants San Francisco 2017 and Hong Kong 2019

by Kendra, Joseph A. , Niendorf, Sandra , Tohma, Kentaro , Landivar, Michael , Ford-Siltz, Lauren A. , Pilewski, Kelsey A. , Parra, Gabriel I.

2024

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Journal Article

Antigenic Characterization of Novel Human Norovirus GII.4 Variants San Francisco 2017 and Hong Kong 2019

Kendra, Joseph A.,

Niendorf, Sandra,

Tohma, Kentaro,

Landivar, Michael,

Ford-Siltz, Lauren A.,

Pilewski, Kelsey A.,

Parra, Gabriel I.

2024

Overview

Norovirus is a major cause of acute gastroenteritis; GII.4 is the predominant strain in humans. Recently, 2 new GII.4 variants, Hong Kong 2019 and San Francisco 2017, were reported. Characterization using GII.4 monoclonal antibodies and serum demonstrated different antigenic profiles for the new variants compared with historical variants.

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Publisher

U.S. National Center for Infectious Diseases,Centers for Disease Control and Prevention

Subject

acute gastroenteritis

/ Antibodies, Monoclonal - immunology

/ Antibodies, Viral - blood

/ Antibodies, Viral - immunology

/ Antigenic Characterization of Novel Human Norovirus GII.4 Variants San Francisco 2017 and Hong Kong 2019

/ Antigens, Viral - genetics

/ Antigens, Viral - immunology