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Genome Wide Association Mapping for Arabinoxylan Content in a Collection of Tetraploid Wheats
by
Waugh, Robbie
, Burton, Rachel A.
, Houston, Kelly
, Blanco, Antonio
, Gadaleta, Agata
, Marcotuli, Ilaria
, Fincher, Geoffrey B.
in
Arabinoxylans
/ Barley
/ Bayes Theorem
/ Biosynthetic Pathways - genetics
/ Bread
/ Breeding
/ Cardiovascular disease
/ Cell walls
/ Chromosome 7
/ Chromosome Mapping
/ Chromosomes
/ Chromosomes, Plant - genetics
/ Conservation
/ Conserved sequence
/ Databases, Genetic
/ Diet
/ Dietary fiber
/ Evolutionary conservation
/ Food
/ Gene Expression Regulation, Plant
/ Gene mapping
/ Gene sequencing
/ Genes
/ Genetic Markers
/ Genetic variability
/ Genetics
/ Genome, Plant
/ Genome-wide association studies
/ Genome-Wide Association Study
/ Genomes
/ Genomics
/ Genotype
/ Genotypes
/ Germplasm
/ Glucan
/ Glucosyltransferase
/ Glycosyl hydrolase
/ Grain
/ Health aspects
/ Health promotion
/ Human nutrition
/ Hydrolase
/ Hydrolases
/ Loci
/ Nutrition
/ Plant breeding
/ Polymorphism, Single Nucleotide - genetics
/ Population
/ Proteins
/ Quantitative genetics
/ Quantitative trait loci
/ Quantitative Trait Loci - genetics
/ Quantitative Trait, Heritable
/ Seeds - genetics
/ Single-nucleotide polymorphism
/ Sorghum
/ Starch
/ Studies
/ Synteny
/ Tetraploidy
/ Triticum
/ Triticum - genetics
/ Triticum aestivum
/ Triticum durum
/ Wheat
/ Xylans - genetics
2015
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Genome Wide Association Mapping for Arabinoxylan Content in a Collection of Tetraploid Wheats
by
Waugh, Robbie
, Burton, Rachel A.
, Houston, Kelly
, Blanco, Antonio
, Gadaleta, Agata
, Marcotuli, Ilaria
, Fincher, Geoffrey B.
in
Arabinoxylans
/ Barley
/ Bayes Theorem
/ Biosynthetic Pathways - genetics
/ Bread
/ Breeding
/ Cardiovascular disease
/ Cell walls
/ Chromosome 7
/ Chromosome Mapping
/ Chromosomes
/ Chromosomes, Plant - genetics
/ Conservation
/ Conserved sequence
/ Databases, Genetic
/ Diet
/ Dietary fiber
/ Evolutionary conservation
/ Food
/ Gene Expression Regulation, Plant
/ Gene mapping
/ Gene sequencing
/ Genes
/ Genetic Markers
/ Genetic variability
/ Genetics
/ Genome, Plant
/ Genome-wide association studies
/ Genome-Wide Association Study
/ Genomes
/ Genomics
/ Genotype
/ Genotypes
/ Germplasm
/ Glucan
/ Glucosyltransferase
/ Glycosyl hydrolase
/ Grain
/ Health aspects
/ Health promotion
/ Human nutrition
/ Hydrolase
/ Hydrolases
/ Loci
/ Nutrition
/ Plant breeding
/ Polymorphism, Single Nucleotide - genetics
/ Population
/ Proteins
/ Quantitative genetics
/ Quantitative trait loci
/ Quantitative Trait Loci - genetics
/ Quantitative Trait, Heritable
/ Seeds - genetics
/ Single-nucleotide polymorphism
/ Sorghum
/ Starch
/ Studies
/ Synteny
/ Tetraploidy
/ Triticum
/ Triticum - genetics
/ Triticum aestivum
/ Triticum durum
/ Wheat
/ Xylans - genetics
2015
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Genome Wide Association Mapping for Arabinoxylan Content in a Collection of Tetraploid Wheats
by
Waugh, Robbie
, Burton, Rachel A.
, Houston, Kelly
, Blanco, Antonio
, Gadaleta, Agata
, Marcotuli, Ilaria
, Fincher, Geoffrey B.
in
Arabinoxylans
/ Barley
/ Bayes Theorem
/ Biosynthetic Pathways - genetics
/ Bread
/ Breeding
/ Cardiovascular disease
/ Cell walls
/ Chromosome 7
/ Chromosome Mapping
/ Chromosomes
/ Chromosomes, Plant - genetics
/ Conservation
/ Conserved sequence
/ Databases, Genetic
/ Diet
/ Dietary fiber
/ Evolutionary conservation
/ Food
/ Gene Expression Regulation, Plant
/ Gene mapping
/ Gene sequencing
/ Genes
/ Genetic Markers
/ Genetic variability
/ Genetics
/ Genome, Plant
/ Genome-wide association studies
/ Genome-Wide Association Study
/ Genomes
/ Genomics
/ Genotype
/ Genotypes
/ Germplasm
/ Glucan
/ Glucosyltransferase
/ Glycosyl hydrolase
/ Grain
/ Health aspects
/ Health promotion
/ Human nutrition
/ Hydrolase
/ Hydrolases
/ Loci
/ Nutrition
/ Plant breeding
/ Polymorphism, Single Nucleotide - genetics
/ Population
/ Proteins
/ Quantitative genetics
/ Quantitative trait loci
/ Quantitative Trait Loci - genetics
/ Quantitative Trait, Heritable
/ Seeds - genetics
/ Single-nucleotide polymorphism
/ Sorghum
/ Starch
/ Studies
/ Synteny
/ Tetraploidy
/ Triticum
/ Triticum - genetics
/ Triticum aestivum
/ Triticum durum
/ Wheat
/ Xylans - genetics
2015
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Genome Wide Association Mapping for Arabinoxylan Content in a Collection of Tetraploid Wheats
Journal Article
Genome Wide Association Mapping for Arabinoxylan Content in a Collection of Tetraploid Wheats
2015
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Overview
Arabinoxylans (AXs) are major components of plant cell walls in bread wheat and are important in bread-making and starch extraction. Furthermore, arabinoxylans are components of soluble dietary fibre that has potential health-promoting effects in human nutrition. Despite their high value for human health, few studies have been carried out on the genetics of AX content in durum wheat.
The genetic variability of AX content was investigated in a set of 104 tetraploid wheat genotypes and regions attributable to AX content were identified through a genome wide association study (GWAS). The amount of arabinoxylan, expressed as percentage (w/w) of the dry weight of the kernel, ranged from 1.8% to 5.5% with a mean value of 4.0%. The GWAS revealed a total of 37 significant marker-trait associations (MTA), identifying 19 quantitative trait loci (QTL) associated with AX content. The highest number of MTAs was identified on chromosome 5A (seven), where three QTL regions were associated with AX content, while the lowest number of MTAs was detected on chromosomes 2B and 4B, where only one MTA identified a single locus. Conservation of synteny between SNP marker sequences and the annotated genes and proteins in Brachypodium distachyon, Oryza sativa and Sorghum bicolor allowed the identification of nine QTL coincident with candidate genes. These included a glycosyl hydrolase GH35, which encodes Gal7 and a glucosyltransferase GT31 on chromosome 1A; a cluster of GT1 genes on chromosome 2B that includes TaUGT1 and cisZog1; a glycosyl hydrolase that encodes a CelC gene on chromosome 3A; Ugt12887 and TaUGT1genes on chromosome 5A; a (1,3)-β-D-glucan synthase (Gsl12 gene) and a glucosyl hydrolase (Cel8 gene) on chromosome 7A.
This study identifies significant MTAs for the AX content in the grain of tetraploid wheat genotypes. We propose that these may be used for molecular breeding of durum wheat varieties with higher soluble fibre content.
Publisher
Public Library of Science,Public Library of Science (PLoS)
Subject
/ Barley
/ Biosynthetic Pathways - genetics
/ Bread
/ Breeding
/ Chromosomes, Plant - genetics
/ Diet
/ Food
/ Gene Expression Regulation, Plant
/ Genes
/ Genetics
/ Genome-wide association studies
/ Genome-Wide Association Study
/ Genomes
/ Genomics
/ Genotype
/ Glucan
/ Grain
/ Loci
/ Polymorphism, Single Nucleotide - genetics
/ Proteins
/ Quantitative Trait Loci - genetics
/ Quantitative Trait, Heritable
/ Single-nucleotide polymorphism
/ Sorghum
/ Starch
/ Studies
/ Synteny
/ Triticum
/ Wheat
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