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Three-Dimensional Structure of Interleukin-2
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Journal Article
Three-Dimensional Structure of Interleukin-2
1987
Overview
Interleukin-2 is an effector protein that participates in modulating the immune response; it has become a focal point for the study of lymphokine structure and function. The three-dimensional structure of the interleukin molecule has been solved to 3.0 angstrom resolution. Interleukin-2 has a novel alpha-helical tertiary structure that suggests one portion of the molecule forms a structural scaffold, which underlies the receptor binding facets of the molecule.
Publisher
The American Association for the Advancement of Science,American Association for the Advancement of Science
Subject
/ Analysis of the immune response. Humoral and cellular immunity
/ Animals
/ Atoms
/ Biological and medical sciences
/ Crystals
/ Fundamental and applied biological sciences. Psychology
/ Interleukin-2 - isolation & purification
/ Lymphokines, interleukins ( function, expression)
/ man
/ Mice
/ Phenyls
/ Proteins
/ Regulatory factors and their cellular receptors
/ Solvents
