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COVID-19 vaccine acceptance and hesitancy in low- and middle-income countries

by Scacco, Alexandra , Asad, Saher , Pare, Touba Bakary , Jaramillo, Sofía , Shapiro, Jacob N , Cabra García, Magarita Rosa , Björkman Nyqvist, Martina , Kamwesigye, Anthony , Trivedi, Bhartendu , Polanco, Laura , Malik, Amyn Abdul , Littman, Rebecca , Tiwana, Hamid Ali , Bosancianu, Constantin Manuel , Warren, Shana S , Nsabimana, Jean Aime , Zafar, Basit , Solís Arce, Julio S , Adeojo, Opeyemi , Svensson, Jakob , Humphreys, Macartan , Kharel, Arjun , Tariq, Ahsan , Meriggi, Niccolò F , Weissinger, Laurin B , Collins, Elliott , Hasanain, Ali , Qureshi, Javaeria Ashraf , Callen, Michael , Cuccaro, Filippo , Armand, Alex , Zhang, Baobao , Vicente, Pedro C , Guariso, Andrea , Anigo, Deborah , Galindo Soria, Mery Len , Malik, Mohammad , Obara, Isaac , Platas, Melina R , Momoh, Fatoma , Syunyaev, Georgiy , Farooqi, Ahsan Zia , Mussa, Imamo , Teachout, Matthieu , Omer, Saad B , Tchibozo, Achille Mignondo , Fatima, Tatheer , Kallon, Sellu , Raheem, Mariam , Borisova, Ekaterina , Cheema, Ali , Karlan, Dean , Shah, Taimur , Bancalari, Antonella , Ramakrishna, Vasudha , Voors, Maarten , Levine, Madison , Shaked, Sarene Eyla , Mobarak, Ahmed Mushfiq , Fracchia, Mattia , Ouéd

in 692/308/174 / 706/689/680 / Biomedical and Life Sciences / Biomedicine / Cancer Research / Coronaviruses / COVID-19 / COVID-19 - prevention & control / COVID-19 - virology / COVID-19 vaccines / COVID-19 Vaccines - administration & dosage / COVID-19 Vaccines - supply & distribution / Developing Countries / Epidemiologie / epidemiology / Forecasts and trends / Health behavior / Health care / Heterogeneity / Humans / Immunization / Income / Infectious Diseases / interdisciplinary studies / International aspects / Low income groups / Medical personnel / Metabolic Diseases / Molecular Medicine / Neurosciences / Pandemics / Patient Acceptance of Health Care / Polls & surveys / SARS-CoV-2 - isolation & purification / Side effects / Southern Hemisphere / Vaccine efficacy / Vaccines

2021

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2021

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2021

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Journal Article

COVID-19 vaccine acceptance and hesitancy in low- and middle-income countries

Scacco, Alexandra,

Asad, Saher,

Pare, Touba Bakary,

Jaramillo, Sofía,

Shapiro, Jacob N,

Cabra García, Magarita Rosa,

Björkman Nyqvist, Martina,

Kamwesigye, Anthony,

Trivedi, Bhartendu,

Polanco, Laura,

Malik, Amyn Abdul,

Littman, Rebecca,

Tiwana, Hamid Ali,

Bosancianu, Constantin Manuel,

Warren, Shana S,

Nsabimana, Jean Aime,

Zafar, Basit,

Solís Arce, Julio S,

Adeojo, Opeyemi,

Svensson, Jakob,

Humphreys, Macartan,

Kharel, Arjun,

Tariq, Ahsan,

Meriggi, Niccolò F,

Weissinger, Laurin B,

Collins, Elliott,

Hasanain, Ali,

Qureshi, Javaeria Ashraf,

Callen, Michael,

Cuccaro, Filippo,

Armand, Alex,

Zhang, Baobao,

Vicente, Pedro C,

Guariso, Andrea,

Anigo, Deborah,

Galindo Soria, Mery Len,

Malik, Mohammad,

Obara, Isaac,

Platas, Melina R,

Momoh, Fatoma,

Syunyaev, Georgiy,

Farooqi, Ahsan Zia,

Mussa, Imamo,

Teachout, Matthieu,

Omer, Saad B,

Tchibozo, Achille Mignondo,

Fatima, Tatheer,

Kallon, Sellu,

Raheem, Mariam,

Borisova, Ekaterina,

Cheema, Ali,

Karlan, Dean,

Shah, Taimur,

Bancalari, Antonella,

Ramakrishna, Vasudha,

Voors, Maarten,

Levine, Madison,

Shaked, Sarene Eyla,

Mobarak, Ahmed Mushfiq,

Fracchia, Mattia,

Ouéd

2021

Overview

Widespread acceptance of COVID-19 vaccines is crucial for achieving sufficient immunization coverage to end the global pandemic, yet few studies have investigated COVID-19 vaccination attitudes in lower-income countries, where large-scale vaccination is just beginning. We analyze COVID-19 vaccine acceptance across 15 survey samples covering 10 low- and middle-income countries (LMICs) in Asia, Africa and South America, Russia (an upper-middle-income country) and the United States, including a total of 44,260 individuals. We find considerably higher willingness to take a COVID-19 vaccine in our LMIC samples (mean 80.3%; median 78%; range 30.1 percentage points) compared with the United States (mean 64.6%) and Russia (mean 30.4%). Vaccine acceptance in LMICs is primarily explained by an interest in personal protection against COVID-19, while concern about side effects is the most common reason for hesitancy. Health workers are the most trusted sources of guidance about COVID-19 vaccines. Evidence from this sample of LMICs suggests that prioritizing vaccine distribution to the Global South should yield high returns in advancing global immunization coverage. Vaccination campaigns should focus on translating the high levels of stated acceptance into actual uptake. Messages highlighting vaccine efficacy and safety, delivered by healthcare workers, could be effective for addressing any remaining hesitancy in the analyzed LMICs.

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Publisher

Springer Nature,Nature Publishing Group US,Nature Publishing Group

Subject

692/308/174

/ 706/689/680

/ Biomedical and Life Sciences