Asset Details
Do you wish to reserve the book?
Intellectual Impairment in School-Age Children Exposed to Manganese from Drinking Water
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Intellectual Impairment in School-Age Children Exposed to Manganese from Drinking Water
Do you wish to request the book?
Intellectual Impairment in School-Age Children Exposed to Manganese from Drinking Water
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Intellectual Impairment in School-Age Children Exposed to Manganese from Drinking Water
2011
Overview
Background: Manganese is an essential nutrient, but in excess it can be a potent neurotoxicant. Despite the common occurrence of manganese in groundwater, the risks associated with this source of exposure are largely unknown. Objectives: Our first aim was to assess the relations between exposure to manganese from drinking water and children's intelligence quotient (IQ). Second, we examined the relations between manganese exposures from water consumption and from the diet with children's hair manganese concentration. Methods: This cross-sectional study included 362 children 6—13 years of age living in communities supplied by groundwater. Manganese concentration was measured in home tap water (MnW) and children's hair (MnH). We estimated manganese intake from water ingestion and the diet using a food frequency questionnaire and assessed IQ with the Wechsler Abbreviated Scale of Intelligence. Results: The median MnW in children's home tap water was 34 µg/L (range, 1-2,700 µg/L). MnH increased with manganese intake from water consumption, but not with dietary manganese intake. Higher MnW and MnH were significantly associated with lower IQ scores. A 10-fold increase in MnW was associated with a decrease of 2.4 IQ points (95% confidence interval: — 3.9 to -0.9; p < 0.01), adjusting for maternal intelligence, family income, and other potential confounders. There was a 6.2-point difference in IQ between children in the lowest and highest MnW quintiles. MnW was more strongly associated with Performance IQ than Verbal IQ. Conclusions: The findings of this cross-sectional study suggest that exposure to manganese at levels common in groundwater is associated with intellectual impairment in children.
Publisher
National Institute of Environmental Health Sciences,US Department of Health and Human Services
Subject
/ Adult and adolescent clinical studies
/ Biological and medical sciences
/ Chemical and industrial products toxicology. Toxic occupational diseases
/ Child
/ Children
/ Diet - statistics & numerical data
/ Environment. Living conditions
/ Environmental Exposure - analysis
/ Environmental Exposure - statistics & numerical data
/ Female
/ Hair
/ Humans
/ Intakes
/ Male
/ Metals and various inorganic compounds
/ Modeling
/ Psychology. Psychoanalysis. Psychiatry
/ Public health. Hygiene-occupational medicine
/ Students - statistics & numerical data
/ Water Pollutants, Chemical - analysis
/ Water Pollutants, Chemical - metabolism
