Asset Details
Do you wish to reserve the book?
Calcium as a Coagonist of Inositol 1,4,5-Trisphosphate-Induced Calcium Release
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Calcium as a Coagonist of Inositol 1,4,5-Trisphosphate-Induced Calcium Release
Do you wish to request the book?
Calcium as a Coagonist of Inositol 1,4,5-Trisphosphate-Induced Calcium Release
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Calcium as a Coagonist of Inositol 1,4,5-Trisphosphate-Induced Calcium Release
1991
Overview
Inositol 1,4,5-trisphosphate (IP$_3$)-induced calcium release from intracellular stores is a regulator of cytosolic-free calcium levels. The subsecond kinetics and regulation of IP$_3$-induced calcium-45 release from synaptosome-derived microsomal vesicles were resolved by rapid superfusion. Extravesicular calcium acted as a coagonist, potentiating the transient IP$_3$-induced release of calcium-45. Thus, rapid elevation of cytosolic calcium levels may trigger IP$_3$-induced calcium release in vivo. Extravesicular calcium also produced a more slowly developing, reversible inhibition of IP$_3$-induced calcium-45 release. Sequential positive and negative feedback regulation by calcium of IP$_3$-induced calcium release may contribute to transients and oscillations of cytosolic-free calcium in vivo.
Publisher
American Society for the Advancement of Science,American Association for the Advancement of Science,The American Association for the Advancement of Science
Subject
Adenosine Triphosphate - pharmacology
/ Animals
/ Biological and medical sciences
/ brain
/ Calcium
/ Fundamental and applied biological sciences. Psychology
/ Heparin
/ inositol 1,4,5-trisphosphate
/ Inositol 1,4,5-Trisphosphate - pharmacology
/ Kinetics
/ Molecular and cellular biology
/ Neurons
/ Rats
