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Adipocytokines and Insulin Resistance: The possible role of lipocalin-2, retinol binding protein-4, and adiponectin
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Adipocytokines and Insulin Resistance: The possible role of lipocalin-2, retinol binding protein-4, and adiponectin
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Journal Article
Adipocytokines and Insulin Resistance: The possible role of lipocalin-2, retinol binding protein-4, and adiponectin
2009
Overview
Conversely, LCN2 has recently been claimed to display anti-inflammatory effects, so that increased LCN2 levels in obesity and insulin resistance may constitute a protective mechanism against inflammation (10). [...] LCN2 upregulated peroxisome proliferatoractivated receptor (PPAR)-γ and its target genes, adiponectin, leptin, fatty acid synthase, and lipoprotein lipase in adipocytes.
Publisher
American Diabetes Association
Subject
Acute-Phase Proteins - genetics
/ Acute-Phase Proteins - metabolism
/ Animals
/ Colony-stimulating factors (Physiology)
/ Diabetes
/ Glucose Intolerance - genetics
/ Humans
/ Insulin
/ Insulin Resistance - genetics
/ Mice
/ Oncogene Proteins - genetics
/ Oncogene Proteins - metabolism
/ Proteins
/ Proto-Oncogene Proteins - genetics
/ Proto-Oncogene Proteins - metabolism
