Asset Details
Do you wish to reserve the book?
Evaluating polymicrobial immune responses in patients suffering from tick-borne diseases
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Evaluating polymicrobial immune responses in patients suffering from tick-borne diseases
Do you wish to request the book?
Evaluating polymicrobial immune responses in patients suffering from tick-borne diseases
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Evaluating polymicrobial immune responses in patients suffering from tick-borne diseases
2018
Overview
There is insufficient evidence to support screening of various tick-borne diseases (TBD) related microbes alongside Borrelia in patients suffering from TBD. To evaluate the involvement of multiple microbial immune responses in patients experiencing TBD we utilized enzyme-linked immunosorbent assay. Four hundred and thirty-two human serum samples organized into seven categories followed Centers for Disease Control and Prevention two-tier Lyme disease (LD) diagnosis guidelines and Infectious Disease Society of America guidelines for post-treatment Lyme disease syndrome. All patient categories were tested for their immunoglobulin M (IgM) and G (IgG) responses against 20 microbes associated with TBD. Our findings recognize that microbial infections in patients suffering from TBDs do not follow the one microbe, one disease Germ Theory as 65% of the TBD patients produce immune responses to various microbes. We have established a causal association between TBD patients and TBD associated co-infections and essential opportunistic microbes following Bradford Hill's criteria. This study indicated an 85% probability that a randomly selected TBD patient will respond to Borrelia and other related TBD microbes rather than to Borrelia alone. A paradigm shift is required in current healthcare policies to diagnose TBD so that patients can get tested and treated even for opportunistic infections.
Publisher
Nature Publishing Group,Nature Publishing Group UK
Subject
/ Borrelia
/ Borrelia burgdorferi - immunology
/ Borrelia burgdorferi - pathogenicity
/ Enzyme-linked immunosorbent assay
/ Humans
/ Immunoglobulin G - immunology
/ Immunoglobulin M - immunology
/ Patients
/ Tick-Borne Diseases - diagnosis
/ Tick-Borne Diseases - immunology
