Asset Details
Do you wish to reserve the book?
Hepatitis C Virus RNA in the Bone Marrow of Patients with Mixed Cryoglobulinemia and in Subjects with Noncryoglobulinemic Chronic Hepatitis Type C
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Hepatitis C Virus RNA in the Bone Marrow of Patients with Mixed Cryoglobulinemia and in Subjects with Noncryoglobulinemic Chronic Hepatitis Type C
Do you wish to request the book?
Hepatitis C Virus RNA in the Bone Marrow of Patients with Mixed Cryoglobulinemia and in Subjects with Noncryoglobulinemic Chronic Hepatitis Type C
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Hepatitis C Virus RNA in the Bone Marrow of Patients with Mixed Cryoglobulinemia and in Subjects with Noncryoglobulinemic Chronic Hepatitis Type C
1995
Overview
Hepatitis C virus (HCV) infection is associated with most mixed cryoglobulinemia (MC) syndromes. In this study, HCV RNA was detected in the peripheral blood mononuclear cells of 11 (73.3%) of 15 patients with MC and in 5 (71.4%) of 7 noncryoglobulinemic patients with chronic hepatitis type C. All patients with cryoglobulinemia and 3 (42.8%) of the 7 without cryoglobulinemia (P <.05) had HCV RNA in bone marrow cells. Subjects in both groups with HCV-positive bone marrow also had HCV RNA in serum. The majority of patients with MC syndromes were infected with HCV subtypes lb and 2a. Two patients with MC had different genotypes in serum and cells. Further studies are needed to determine which bone marrow cell population is preferentially infected by HCV and to determine if this phenomenon is involved in inducing the production of cryoglobulins.
