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Renal Cell Carcinoma: Overview
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Book Chapter
Renal Cell Carcinoma: Overview
2015,2014
Overview
Renal cell carcinoma is histologically heterogeneous and can be considered as a group of closely related but distinct tumour types that differ in histopathology and genetic findings. In most cases renal tumours occur sporadically but a minority occur in individuals with an inherited predisposition to kidney cancer and, sometimes, other tumours. Knowledge of the molecular basis of inherited kidney tumours has provided important insights into the key cellular pathways that are disordered in the pathogenesis of kidney cancer. Here we review the relationship between aetiology, histopathology and molecular characteristics of differing subtypes of renal cell carcinoma.
Publisher
Springer London, Limited,Springer London
Subject
ISBN
0857294814, 9780857294814
