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Adult-onset Still’s disease with macrophage activation syndrome successfully treated with a combination of methotrexate and etanercept
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Adult-onset Still’s disease with macrophage activation syndrome successfully treated with a combination of methotrexate and etanercept
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Journal Article
Adult-onset Still’s disease with macrophage activation syndrome successfully treated with a combination of methotrexate and etanercept
2012
Overview
We report a 16-year-old female case of intractable adult-onset Still’s disease accompanied by macrophage activation syndrome, who went into full remission after switching from infliximab to etanercept. Although the disease promptly relapsed when etanercept was discontinued, she again responded fully upon the reintroduction of etanercept. Furthermore, the effect of etanercept was apparently enhanced by combining it with a sufficient dose of methotrexate. This combination therapy should be considered as one of treatment options for the disease.
Publisher
Springer Japan,Informa Healthcare
Subject
/ Female
/ Humans
/ Immunoglobulin G - therapeutic use
/ Juvenile rheumatoid arthritis
/ Macrophage Activation Syndrome - drug therapy
/ Macrophage Activation Syndrome - immunology
/ Macrophage Activation Syndrome - pathology
/ Medicine
/ Methotrexate - therapeutic use
/ Receptors, Tumor Necrosis Factor - therapeutic use
/ Still's Disease, Adult-Onset - drug therapy
/ Still's Disease, Adult-Onset - immunology
