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Impact of etiology of cirrhosis on the survival of patients diagnosed with hepatocellular carcinoma during surveillance
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Impact of etiology of cirrhosis on the survival of patients diagnosed with hepatocellular carcinoma during surveillance
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Impact of etiology of cirrhosis on the survival of patients diagnosed with hepatocellular carcinoma during surveillance
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Journal Article
Impact of etiology of cirrhosis on the survival of patients diagnosed with hepatocellular carcinoma during surveillance
2007
Overview
Although the etiology of liver disease affects the features of hepatocellular carcinoma (HCC) diagnosed during surveillance, it is not known whether it influences patients' survival. We analyzed the impact of etiology on the characteristics and outcome of HCC detected during surveillance.
In this cohort study, 742 patients with HCC detected during semiannual or annual surveillance were selected from the ITA.LI.CA database, including 1,834 consecutive patients observed in three primary and seven tertiary care settings for HCC. Patients were grouped according to etiology: hepatitis B virus (HBV, 87), hepatitis C virus (HCV, 461), alcohol (59), and multietiology (135).
In all etiologic groups, most HCCs were unifocal (51-68%) and most of them were
Publisher
Blackwell Publishing,Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
Subject
/ Alcohol Drinking - adverse effects
/ Biological and medical sciences
/ Carcinoma, Hepatocellular - epidemiology
/ Carcinoma, Hepatocellular - etiology
/ Carcinoma, Hepatocellular - pathology
/ Carcinoma, Hepatocellular - virology
/ Female
/ Gastroenterology. Liver. Pancreas. Abdomen
/ Humans
/ Liver Cirrhosis - epidemiology
/ Liver Neoplasms - epidemiology
/ Liver. Biliary tract. Portal circulation. Exocrine pancreas
/ Male
/ Tumors
