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Dynamic mechanical analysis and morphological characterization of electrospun polycaprolactone, gelatin and PCL/Gelatin (50/50) scaffolds
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Dynamic mechanical analysis and morphological characterization of electrospun polycaprolactone, gelatin and PCL/Gelatin (50/50) scaffolds
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Journal Article
Dynamic mechanical analysis and morphological characterization of electrospun polycaprolactone, gelatin and PCL/Gelatin (50/50) scaffolds
2026
Overview
This research concerns the production of three electrospun scaffolds: the first produced from a synthetic polymer, polycaprolactone (PCL); the second from a natural polymer, porcine gelatin type A, crosslinked with glutaraldehyde vapors (G); and the third from a mixture of both in a 50/50 (m/m) PCL/G composition. The objective of this paper is to define the operating parameters for electrospinning the substances and to perform a mechanical evaluation of the resulting scaffolds using Dynamic Mechanical Analysis (DMA). Initially, defective scaffolds with lumpy fibers were obtained, but adjusting the variables resulted in scaffolds with a smooth, porous fibrous morphology. DMA was applied to the three scaffolds, and the storage modulus (E’), loss modulus (E’’), and damping factor (tan δ) were determined for each to estimate the state transition temperature. The main results yielded matrices with suitable morphologies and viscoelastic behavior, making them promising candidates for use in tissue regeneration.
Publisher
Universidad de Antioquia
Subject
