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Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity

by Lee, Hailey R. , Labora, Amanda N. , Lok, Vincent , Ribas, Antoni , Donahue, Timothy R. , Li, Luyi , Li, Suwen , Mandl, Hanna K. , Radu, Caius G. , Wu, Nanping , Bantia, Shanta , Abt, Evan R. , Abril-Rodriguez, Gabriel , Cho, Arthur , Lam, Alex K. , Rashid, Khalid , Hugo, Willy , Mehrling, Thomas , Creech, Amanda L. , Wu, Ting-Ting , Rezek, Valerie , Rosser, Ethan W. , Mittelman, Steven D. , Le, Thuc M. , Crooks, Gay M.

in Autoimmune diseases / Genetic aspects / Health aspects / Immunological deficiency syndromes / Phosphorylase / Physiological aspects / Prevention / Purine nucleotides / TLR7

2022

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Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity

in Autoimmune diseases / Genetic aspects / Health aspects / Immunological deficiency syndromes / Phosphorylase / Physiological aspects / Prevention / Purine nucleotides / TLR7

2022

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Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity

in Autoimmune diseases / Genetic aspects / Health aspects / Immunological deficiency syndromes / Phosphorylase / Physiological aspects / Prevention / Purine nucleotides / TLR7

2022

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