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AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model

AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model

by Verhaert, Jens , Creemers, Eline , De Strooper, Bart , Wierda, Keimpe , Marneffe, Catherine , Saito, Takashi , Dewilde, Maarten , Marino, Marika , Callaerts‐Vegh, Zsuzsanna , Rincon, Melvin Y , Wouters, Yessica , Duqué, Sandra I , Yshii, Lidia , Vincke, Cécile , Holt, Matthew G , Zhou, Lujia , Voytyuk, Iryna , Liston, Adrian , Wahis, Jérôme , Muyldermans, Serge , Levites, Yona , Golde, Todd E , Saido, Takaomi C

in AAV / Alzheimer Disease / Alzheimer’s disease / Amyloid beta-Peptides / Amyloid Precursor Protein Secretases / Animals / Anti-BACE1 / Aspartic Acid Endopeptidases / Blood-Brain Barrier / Dependovirus / Disease Models, Animal / Genetic Vectors / Genetics / Medicine (General) / Mice / Mice, Transgenic / QH426-470 / R5-920 / Single-Domain Antibodies / VHH

2022

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AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model

by Verhaert, Jens , Creemers, Eline , De Strooper, Bart , Wierda, Keimpe , Marneffe, Catherine , Saito, Takashi , Dewilde, Maarten , Marino, Marika , Callaerts‐Vegh, Zsuzsanna , Rincon, Melvin Y , Wouters, Yessica , Duqué, Sandra I , Yshii, Lidia , Vincke, Cécile , Holt, Matthew G , Zhou, Lujia , Voytyuk, Iryna , Liston, Adrian , Wahis, Jérôme , Muyldermans, Serge , Levites, Yona , Golde, Todd E , Saido, Takaomi C

in AAV / Alzheimer Disease / Alzheimer’s disease / Amyloid beta-Peptides / Amyloid Precursor Protein Secretases / Animals / Anti-BACE1 / Aspartic Acid Endopeptidases / Blood-Brain Barrier / Dependovirus / Disease Models, Animal / Genetic Vectors / Genetics / Medicine (General) / Mice / Mice, Transgenic / QH426-470 / R5-920 / Single-Domain Antibodies / VHH

2022

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AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model

AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model

by Verhaert, Jens , Creemers, Eline , De Strooper, Bart , Wierda, Keimpe , Marneffe, Catherine , Saito, Takashi , Dewilde, Maarten , Marino, Marika , Callaerts‐Vegh, Zsuzsanna , Rincon, Melvin Y , Wouters, Yessica , Duqué, Sandra I , Yshii, Lidia , Vincke, Cécile , Holt, Matthew G , Zhou, Lujia , Voytyuk, Iryna , Liston, Adrian , Wahis, Jérôme , Muyldermans, Serge , Levites, Yona , Golde, Todd E , Saido, Takaomi C

in AAV / Alzheimer Disease / Alzheimer’s disease / Amyloid beta-Peptides / Amyloid Precursor Protein Secretases / Animals / Anti-BACE1 / Aspartic Acid Endopeptidases / Blood-Brain Barrier / Dependovirus / Disease Models, Animal / Genetic Vectors / Genetics / Medicine (General) / Mice / Mice, Transgenic / QH426-470 / R5-920 / Single-Domain Antibodies / VHH

2022

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AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model

Journal Article

AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model

Verhaert, Jens,

Creemers, Eline,

De Strooper, Bart,

Wierda, Keimpe,

Marneffe, Catherine,

Saito, Takashi,

Dewilde, Maarten,

Marino, Marika,

Callaerts‐Vegh, Zsuzsanna,

Rincon, Melvin Y,

Wouters, Yessica,

Duqué, Sandra I,

Yshii, Lidia,

Vincke, Cécile,

Holt, Matthew G,

Zhou, Lujia,

Voytyuk, Iryna,

Liston, Adrian,

Wahis, Jérôme,

Muyldermans, Serge,

Levites, Yona,

Golde, Todd E,

Saido, Takaomi C

2022

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Publisher

Springer Science and Business Media LLC

Subject

/ Alzheimer Disease

/ Alzheimer’s disease

/ Amyloid beta-Peptides

/ Amyloid Precursor Protein Secretases

/ Aspartic Acid Endopeptidases

/ Blood-Brain Barrier

/ Disease Models, Animal

/ Genetic Vectors

/ Medicine (General)

/ Mice, Transgenic

/ Single-Domain Antibodies

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