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Radiation plus intensive systemic therapy improves outcomes in prostate cancer subset
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Radiation plus intensive systemic therapy improves outcomes in prostate cancer subset
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Journal Article
Radiation plus intensive systemic therapy improves outcomes in prostate cancer subset
2023
Overview
During ASCO Annual Meeting, Bossi presented the results of a second preplanned primary endpoint analysis to assess the effect of prostate irradiation on safety and outcomes among men with low-volume disease receiving intensified systemic therapy. The 2x2 factorial design study randomly assigned participants in a 1:1:1:1 ratio to standard of care (ADT plus docetaxel), standard of care plus abiraterone, standard of care plus radiotherapy of the primary tumor, or standard of care plus abiraterone and radiotherapy of the primary tumor. In terms of incorporating prostate radiation into treatment for lowvolume de novo metastatic prostate cancer, we must be careful when interpreting the data in current practice conditions with routine use of much more sensitive imaging tests, such as PSMA PET.
Publisher
SLACK INCORPORATED
Subject
