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Alarmins and Emerging Cytokines in COPD: Histopathological Insights and Novel Therapeutic Targets
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Alarmins and Emerging Cytokines in COPD: Histopathological Insights and Novel Therapeutic Targets
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Journal Article
Alarmins and Emerging Cytokines in COPD: Histopathological Insights and Novel Therapeutic Targets
2025
Overview
Among these, IL-33 has been the most extensively studied in animal and in vitro models, consistently demonstrating a pro-inflammatory role in COPD (5). COPD diagnosis was confirmed by pulmonary function tests according to American Thoracic Society (ATS) and European Respiratory Society (ERS) guidelines. [...]our study demonstrates that IL-33 and IL-40 are upregulated, while IL-41 is downregulated in COPD lung tissue.
Publisher
Firenze University Press Università degli Studi di Firenze
