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Sequence analysis of Escherichia coli O157:H7 bacteriophage V10 and identification of a phage-encoded immunity protein that modifies the O157 antigen
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Sequence analysis of Escherichia coli O157:H7 bacteriophage V10 and identification of a phage-encoded immunity protein that modifies the O157 antigen
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Sequence analysis of Escherichia coli O157:H7 bacteriophage V10 and identification of a phage-encoded immunity protein that modifies the O157 antigen
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Journal Article
Sequence analysis of Escherichia coli O157:H7 bacteriophage V10 and identification of a phage-encoded immunity protein that modifies the O157 antigen
2009
Overview
AbstractBacteriophage V10 is a temperate phage, which specifically infects Escherichia coli O157:H7. The nucleotide sequence of the V10 genome is 39104bp long and contains 55 predicted genes. V10 is closely related to two previously sequenced phages, the Salmonella enterica serovar Anatum (Group E1) phage e15 and a prophage from E. coli APEC O1. The attachment site of V10, like those of its two closest relatives, overlaps the 3' end of guaA in the host chromosome. V10 encodes an O-acetyltransferase, which modifies the O157 antigen. This modification is sufficient to block V10 superinfection, indicating that the O157 antigen is most likely the V10 receptor.
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