Asset Details
Do you wish to reserve the book?
The Streptococcus pyogenes Rgg2/Rgg3 quorum sensing system causes global suppression of macrophage inflammatory programs via an intranuclear mechanism
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
The Streptococcus pyogenes Rgg2/Rgg3 quorum sensing system causes global suppression of macrophage inflammatory programs via an intranuclear mechanism
Do you wish to request the book?
The Streptococcus pyogenes Rgg2/Rgg3 quorum sensing system causes global suppression of macrophage inflammatory programs via an intranuclear mechanism
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
The Streptococcus pyogenes Rgg2/Rgg3 quorum sensing system causes global suppression of macrophage inflammatory programs via an intranuclear mechanism
2025
Overview
Streptococcus pyogenes is a ubiquitous pathogen that causes over 600 million infections every year and 500,000 to 1 million fatalities. While in developed countries, it is generally known to cause mild conditions such as pharyngitis, it can also manifest as severe infections, such as necrotizing fasciitis and septic arthritis, and lead to post-infectious sequelae including rheumatic heart disease and glomerulonephritis. Elucidating new mechanisms of virulence in this organism, including how it evades and suppresses immune responses, is critical in understanding its pathogenicity and epidemiology, as well as identifying novel treatment avenues in this era of multidrug-resistant bacteria. In this study, we characterize the broad spectrum by which GAS modulates the host innate immune response and begin to uncover host pathways that the bacteria can use or inhibit for its survival.
Publisher
American Society for Microbiology,American Society for Microbiology (ASM)
Subject
/ Bacterial Proteins - genetics
/ Bacterial Proteins - metabolism
/ Biofilms
/ Genes
/ Histones
/ Humans
/ Mice
/ Microbial Physiology and Genetics
/ Principal components analysis
/ Proteins
/ Quorum Sensing and Regulation
/ Quorum Sensing in Gram-Positive Bacteria
/ Streptococcal Infections - immunology
/ Streptococcal Infections - microbiology
/ Streptococcus pyogenes - genetics
/ Streptococcus pyogenes - immunology
/ Streptococcus pyogenes - pathogenicity
/ Streptococcus pyogenes - physiology
