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Highlights of the 14th International Bordetella Symposium

by Kampmann, Beate , Sebo, Peter , Munoz Navarrete, Kevin , Mattoo, Seema , Diavatopoulos, Dimitri A. , Mills, Kingston H. G. , Locht, Camille , Gorringe, Andrew , Harvill, Eric T. , Rodriguez, María Eugenia , Edwards, Kathryn M. , Gestal, Monica C. , Kamanová, Jana , Preston, Andrew , Scanlon, Karen M. , Dubey, Purnima

in Antibodies / Antigens / Babies / Biomarkers / Bordetella / Bordetella pertussis / Bordetella pertussis - immunology / Clinical aspects / Clinical trials / Congresses as Topic / Epidemiology / Female / Global Health / Humans / Immune response / Immunity (Disease) / Infant, Newborn / Infections / Infectious diseases / Kinases / Ligands / Medical research / Meeting Review / Mothers / pathogenesis / Pathogens / Pertussis / Pertussis Vaccine - administration & dosage / Pertussis Vaccine - immunology / Pregnancy / Proteins / Tetanus / Toxins / Vaccination / Vaccines / Virulence / Whooping cough / Whooping Cough - epidemiology / Whooping Cough - microbiology / Whooping Cough - prevention & control / Womens health

2025

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2025

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2025

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Journal Article

Highlights of the 14th International Bordetella Symposium

Kampmann, Beate,

Sebo, Peter,

Munoz Navarrete, Kevin,

Mattoo, Seema,

Diavatopoulos, Dimitri A.,

Mills, Kingston H. G.,

Locht, Camille,

Gorringe, Andrew,

Harvill, Eric T.,

Rodriguez, María Eugenia,

Edwards, Kathryn M.,

Gestal, Monica C.,

Kamanová, Jana,

Preston, Andrew,

Scanlon, Karen M.,

Dubey, Purnima

2025

Overview

Pertussis, or whooping cough, is a highly contagious and acute respiratory illness caused primarily by the gram-negative coccobacillus . Despite near-universal vaccination, pertussis remains one of the least-controlled vaccine-preventable infectious diseases. Since 2023, pertussis incidence has been rising, and widespread pertussis outbreaks have resurged in many countries. In response to these emerging challenges, almost 300 experts from institutions across 24 countries convened at the 14th International Symposium in Prague, Czech Republic, from 24 to 28 June 2024 to discuss pertussis epidemiology and research and strategies to mitigate the global pertussis burden. We present here the highlights of the symposium, comprising epidemiological and clinical aspects of infections, results of clinical trials of pertussis vaccination in pregnant women and effectiveness of maternal vaccination in protecting newborn infants in Africa and Europe, the controlled human infection model (CHIM), and the latest insights into the biology, immunology, and pathogenesis of infection.

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Publisher

American Society for Microbiology

Subject

/ Babies

/ Bordetella pertussis

/ Bordetella pertussis - immunology