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Journal Article
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2023
Overview
Long term survivors of childhood cancer At the beginning of Lucina’s career, 5 year survival rates for many childhood cancers were not great, but over the last few decades this has improved significantly with overall survival rates at 5 years being over 85%. Survivors 40 years or more from diagnosis experienced 131 excess health-related deaths per 10 000 person-years (95% CI 111 to 163), including those due to the top three causes of health-related death in the general population: cancer, heart disease and cerebrovascular disease. Blood cultures were obtained from 75.9% (523/689) of patients, of which 510 were available for review and were positive in 70/510 (13.7%; 95% CI, confidence interval (CI), 10.9–17.0) of children and in 70/689 (10.2%; 95% CI, 8.0 to 12.7%) of the entire cohort.
