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Apolipoprotein E: non-cognitive symptoms and cognitive decline in late onset Alzheimer’s disease
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Apolipoprotein E: non-cognitive symptoms and cognitive decline in late onset Alzheimer’s disease
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Journal Article
Apolipoprotein E: non-cognitive symptoms and cognitive decline in late onset Alzheimer’s disease
1997
Overview
Holmes et al 1 presented interesting data suggesting that the presence of an apolipoprotein E (ApoE) [epsilon]4 allele did not effect the rate of progression of cognitive impairment. A detailed description of the methodology is given elsewhere. 2 ApoE genotyping was performed on genomic DNA extracted from whole blood samples according to established procedures. 3 The mean age of the patients was 79; 38 (75%) were women and they had mean CAMCOG scores of 48.
Publisher
BMJ Publishing Group LTD
