Asset Details
Do you wish to reserve the book?
Persistent low concentrations of antiepileptics in a critically ill paediatric patient: an example of multiple potential drug interactions
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Persistent low concentrations of antiepileptics in a critically ill paediatric patient: an example of multiple potential drug interactions
Do you wish to request the book?
Persistent low concentrations of antiepileptics in a critically ill paediatric patient: an example of multiple potential drug interactions
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Persistent low concentrations of antiepileptics in a critically ill paediatric patient: an example of multiple potential drug interactions
2025
Overview
A middle childhood boy with epilepsy exhibited persistent low concentrations of valproic acid, lamotrigine and topiramate for over 1 month, primarily due to pharmacokinetic interactions involving fosphenytoin, meropenem and phenobarbital. Awareness of these clinically significant interactions is crucial for ensuring effective seizure control. However, further research is needed to establish optimal evidence-based treatment strategies in complex paediatric cases.
Publisher
BMJ Publishing Group Ltd,BMJ Publishing Group LTD,BMJ Publishing Group
Subject
/ Acids
/ Anticonvulsants - administration & dosage
/ Anticonvulsants - pharmacokinetics
/ Anticonvulsants - therapeutic use
/ Child
/ Delirium
/ Enzymes
/ Epilepsy
/ Fructose - analogs & derivatives
/ Humans
/ Male
/ Morphine
/ Ostomy
/ Paediatrics (drugs and medicines)
/ Phenobarbital - pharmacokinetics
/ Phenobarbital - therapeutic use
/ Phenytoin - analogs & derivatives
/ Phenytoin - pharmacokinetics
/ Plasma
/ Triazines - pharmacokinetics
