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Choroidal detachment induced by dorzolamide 20 years after cataract surgery
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Choroidal detachment induced by dorzolamide 20 years after cataract surgery
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Journal Article
Choroidal detachment induced by dorzolamide 20 years after cataract surgery
2002
Overview
Comment Selecting an appropriate pharmacological intervention for a patient with OH can reduce IOP by decreasing aqueous humour production by the ciliary processes-for example, carbonic anhydrase (CA) inhibitors. Because of its efficacy, the β adrenergic blocker-for example, timolol, is the gold standard compared with the other treatment. The mechanism of choroidal detachment with dorzolamide is probably due to hypotony caused by the reduction of intraocular pressure by the combination of timolol and dorzolamide. 1, 5 This mechanism has been mentioned in cases of choroidal detachment caused by latanoprost, a prostaglandin analogue used topically to reduce IOP, reported by Marques after filtration surgery. 6 Another case of choroidal detachment has been reported in a patient who underwent left extracapsular cataract extraction with topically latanoprost prescribed immediately postoperatively. 7 Ocular surgery, even if there is a history, seems to increase the risk of choroidal detachment when used as a pharmacological aqueous humour suppressant therapy-for example, dorzolamide or the combination of timolol and dorzolamide.
Publisher
BMJ Publishing Group LTD,Copyright 2002 British Journal of Ophthalmology
