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First trimester cerebral appearance in the presence of closed spina bifida with myelomeningocele, part of the oeis complex
by
Zorila, Lucian George
, Ungureanu, Delia Roxana
, Iliescu, Dominic Gabriel
, Capitanescu, Razvan Grigoras
in
Abdomen
/ Abnormalities, Multiple - diagnosis
/ Aborted Fetus - pathology
/ Abortion, Eugenic - methods
/ Adult
/ anomaly scan
/ Anus
/ body
/ Brain - diagnostic imaging
/ Case reports
/ Defects
/ Diagnostic Errors - prevention & control
/ Female
/ Fetus - diagnostic imaging
/ Fetuses
/ Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect
/ first trimester
/ Gestational Age
/ Humans
/ Medical diagnosis
/ Medical prognosis
/ Meningomyelocele
/ OEIS (omphalocele-exstrophy-imperforate anus-spinal defects)
/ Pathology
/ Pregnancy
/ Pregnancy Trimester, First
/ Prenatal Care - methods
/ prenatal diagnosis
/ Signs
/ Skin
/ Skull - diagnostic imaging
/ Spina bifida
/ Spina Bifida Cystica - diagnosis
/ Spinal cord
/ Ultrasonic imaging
/ Ultrasonography, Prenatal - methods
/ Umbilical cord
2020
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First trimester cerebral appearance in the presence of closed spina bifida with myelomeningocele, part of the oeis complex
by
Zorila, Lucian George
, Ungureanu, Delia Roxana
, Iliescu, Dominic Gabriel
, Capitanescu, Razvan Grigoras
in
Abdomen
/ Abnormalities, Multiple - diagnosis
/ Aborted Fetus - pathology
/ Abortion, Eugenic - methods
/ Adult
/ anomaly scan
/ Anus
/ body
/ Brain - diagnostic imaging
/ Case reports
/ Defects
/ Diagnostic Errors - prevention & control
/ Female
/ Fetus - diagnostic imaging
/ Fetuses
/ Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect
/ first trimester
/ Gestational Age
/ Humans
/ Medical diagnosis
/ Medical prognosis
/ Meningomyelocele
/ OEIS (omphalocele-exstrophy-imperforate anus-spinal defects)
/ Pathology
/ Pregnancy
/ Pregnancy Trimester, First
/ Prenatal Care - methods
/ prenatal diagnosis
/ Signs
/ Skin
/ Skull - diagnostic imaging
/ Spina bifida
/ Spina Bifida Cystica - diagnosis
/ Spinal cord
/ Ultrasonic imaging
/ Ultrasonography, Prenatal - methods
/ Umbilical cord
2020
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First trimester cerebral appearance in the presence of closed spina bifida with myelomeningocele, part of the oeis complex
by
Zorila, Lucian George
, Ungureanu, Delia Roxana
, Iliescu, Dominic Gabriel
, Capitanescu, Razvan Grigoras
in
Abdomen
/ Abnormalities, Multiple - diagnosis
/ Aborted Fetus - pathology
/ Abortion, Eugenic - methods
/ Adult
/ anomaly scan
/ Anus
/ body
/ Brain - diagnostic imaging
/ Case reports
/ Defects
/ Diagnostic Errors - prevention & control
/ Female
/ Fetus - diagnostic imaging
/ Fetuses
/ Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect
/ first trimester
/ Gestational Age
/ Humans
/ Medical diagnosis
/ Medical prognosis
/ Meningomyelocele
/ OEIS (omphalocele-exstrophy-imperforate anus-spinal defects)
/ Pathology
/ Pregnancy
/ Pregnancy Trimester, First
/ Prenatal Care - methods
/ prenatal diagnosis
/ Signs
/ Skin
/ Skull - diagnostic imaging
/ Spina bifida
/ Spina Bifida Cystica - diagnosis
/ Spinal cord
/ Ultrasonic imaging
/ Ultrasonography, Prenatal - methods
/ Umbilical cord
2020
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First trimester cerebral appearance in the presence of closed spina bifida with myelomeningocele, part of the oeis complex
Journal Article
First trimester cerebral appearance in the presence of closed spina bifida with myelomeningocele, part of the oeis complex
2020
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Overview
Our communication presents a prenatally detected case with severe spinal defect detected in the first trimester of pregnancy, accompanied by a large skin-covered myelomeningocele but normal cranio-cerebral structural appearance.These findings suggest that in the first trimester, the extent of the spinal defect, the cerebrospinal fluid leakage to a large, but skin-covered, meningocele and fixation of the spinal cord at the lesion are not sufficient to determine downward hindbrain displacement and the development of secondary signs for open spina bifida.Therefore, we suggest a careful evaluation of the fetal cerebral features if a meningocele is detected. The presence of the skin covering the lesion may not be evident in the first trimester, but the absence of intracranial open spina bifida markers may indicate a ‘closed’ spinal defect, which generally associates a good neurological outcome. Also, studies aimed to investigate the accuracy of the intracranial features for open spina bifida detection should consider the possibility of ‘closed’ myelomeningoceles to avoid incorrect correlations.
Publisher
BMJ Publishing Group Ltd,BMJ Publishing Group LTD,BMJ Publishing Group
Subject
/ Abnormalities, Multiple - diagnosis
/ Adult
/ Anus
/ body
/ Defects
/ Diagnostic Errors - prevention & control
/ Female
/ Fetuses
/ Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect
/ Humans
/ OEIS (omphalocele-exstrophy-imperforate anus-spinal defects)
/ Signs
/ Skin
/ Spina Bifida Cystica - diagnosis
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