Asset Details
Do you wish to reserve the book?
Intracellular calcium and pathogenesis and antenatal diagnosis of Duchenne muscular dystrophy
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Intracellular calcium and pathogenesis and antenatal diagnosis of Duchenne muscular dystrophy
Do you wish to request the book?
Intracellular calcium and pathogenesis and antenatal diagnosis of Duchenne muscular dystrophy
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Intracellular calcium and pathogenesis and antenatal diagnosis of Duchenne muscular dystrophy
1980
Overview
One of the earliest and most important abnormalities of fetal muscle in Duchenne muscular dystrophy is an increase in eosinophilic fibres (those that stain darkly with eosin). A study of normal and at-risk male fetuses after abortion was carried out, which showed that these eosinophilic fibres contain increased intracellular calcium, which suggests that this is an early biochemical change in the disorder. Since increased intracellular calcium would account for various biochemical and clinical features of the disease, it may be related to the primary defect. Thus an increase in muscle fibres containing increased intracellular calcium in at-risk fetuses may provide an additional means of assessing the validity of any future presumptive antenatal test for Duchenne muscular dystrophy.
Publisher
British Medical Journal Publishing Group,British Medical Association,BMJ Publishing Group LTD
Subject
