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Sensitization patterns and minimum screening panels for aeroallergens in self-reported allergic rhinitis in China
by
Ma, Siyuan
, Bachert, Claus
, Liu, Zhongyan
, Bousquet, Jean
, Zhang, Luo
, Cao, Feifei
, He, Fei
, Lou, Hongfei
, Zhao, Yan
, Wang, Chengshuo
in
692/1807/1809
/ 692/699/1785
/ 96/1
/ Adolescent
/ Adult
/ Aerosols - adverse effects
/ Aged
/ Allergens
/ Allergens - immunology
/ Allergic rhinitis
/ Allergies
/ Child
/ China - epidemiology
/ Comorbidity
/ Dander
/ Female
/ House dust
/ Humanities and Social Sciences
/ Humans
/ Immunization
/ Life Sciences
/ Male
/ Middle Aged
/ multidisciplinary
/ Nose
/ Pollen
/ Population Surveillance
/ Prevalence
/ Rhinitis
/ Rhinitis, Allergic - diagnosis
/ Rhinitis, Allergic - epidemiology
/ Rhinitis, Allergic - immunology
/ Risk Factors
/ Science
/ Science (multidisciplinary)
/ Self Report
/ Skin Tests
/ Young Adult
2017
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Sensitization patterns and minimum screening panels for aeroallergens in self-reported allergic rhinitis in China
by
Ma, Siyuan
, Bachert, Claus
, Liu, Zhongyan
, Bousquet, Jean
, Zhang, Luo
, Cao, Feifei
, He, Fei
, Lou, Hongfei
, Zhao, Yan
, Wang, Chengshuo
in
692/1807/1809
/ 692/699/1785
/ 96/1
/ Adolescent
/ Adult
/ Aerosols - adverse effects
/ Aged
/ Allergens
/ Allergens - immunology
/ Allergic rhinitis
/ Allergies
/ Child
/ China - epidemiology
/ Comorbidity
/ Dander
/ Female
/ House dust
/ Humanities and Social Sciences
/ Humans
/ Immunization
/ Life Sciences
/ Male
/ Middle Aged
/ multidisciplinary
/ Nose
/ Pollen
/ Population Surveillance
/ Prevalence
/ Rhinitis
/ Rhinitis, Allergic - diagnosis
/ Rhinitis, Allergic - epidemiology
/ Rhinitis, Allergic - immunology
/ Risk Factors
/ Science
/ Science (multidisciplinary)
/ Self Report
/ Skin Tests
/ Young Adult
2017
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Sensitization patterns and minimum screening panels for aeroallergens in self-reported allergic rhinitis in China
by
Ma, Siyuan
, Bachert, Claus
, Liu, Zhongyan
, Bousquet, Jean
, Zhang, Luo
, Cao, Feifei
, He, Fei
, Lou, Hongfei
, Zhao, Yan
, Wang, Chengshuo
in
692/1807/1809
/ 692/699/1785
/ 96/1
/ Adolescent
/ Adult
/ Aerosols - adverse effects
/ Aged
/ Allergens
/ Allergens - immunology
/ Allergic rhinitis
/ Allergies
/ Child
/ China - epidemiology
/ Comorbidity
/ Dander
/ Female
/ House dust
/ Humanities and Social Sciences
/ Humans
/ Immunization
/ Life Sciences
/ Male
/ Middle Aged
/ multidisciplinary
/ Nose
/ Pollen
/ Population Surveillance
/ Prevalence
/ Rhinitis
/ Rhinitis, Allergic - diagnosis
/ Rhinitis, Allergic - epidemiology
/ Rhinitis, Allergic - immunology
/ Risk Factors
/ Science
/ Science (multidisciplinary)
/ Self Report
/ Skin Tests
/ Young Adult
2017
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Sensitization patterns and minimum screening panels for aeroallergens in self-reported allergic rhinitis in China
Journal Article
Sensitization patterns and minimum screening panels for aeroallergens in self-reported allergic rhinitis in China
2017
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Overview
Optimization of skin prick test (SPT) panels, especially in view of significant differences in sensitizations patterns within different geographical areas, is an unmet need within China. Our aim was to assess the patterns and clinical relevance of aeroallergen sensitizations in allergic rhinitis (AR) and define the minimal battery of SPT allergens, classified according to the Köppen-Geiger climate map. Overall, 7148 subjects with self-reported AR completed a standard questionnaire and were assessed for sensitization to relevant allergens by SPT. 6340 (88.7%) patients had at least one positive skin prick reaction, and demonstrated unique sensitization patterns by stratification with age, gender, and geographic region. Sensitization to house dust mites (HDM) was highest in south China, whereas the three most prevalent aeroallergens were mugwort, ragweed and dandelion pollen in north-west China. Higher sensitization rates and multiple sensitizations were associated with AR comorbidities. Eight allergens (
Der f
, mugwort,
Blatella
, hazel, goosefoot,
Penicillium notatum
, animal dander and
Der p
) allowed identification >96% of sensitized subjects in central China. Differences in optimal panels were observed between regions, with five to six allergens being sufficient for north-east, north-west and south China. These SPT panels may provide a cost-effective tool for screening sensitized patients in China.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
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