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Enhanced recovery after surgery (ERAS) pathway for primary hip and knee arthroplasty: study protocol for a randomized controlled trial
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Enhanced recovery after surgery (ERAS) pathway for primary hip and knee arthroplasty: study protocol for a randomized controlled trial
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Journal Article
Enhanced recovery after surgery (ERAS) pathway for primary hip and knee arthroplasty: study protocol for a randomized controlled trial
2019
Overview
Background
With the substantially growing trend of the aging populations in China and the rest of the world, the number of total hip and total knee arthroplasty (THA and TKA) cases are increasing dramatically. It is important to develop practical strategies to improve the quality of healthcare and better outcome for patients undergoing THA and TKA. Enhanced recovery after surgery (ERAS) pathways have been reported to promote earlier recovery and be beneficial for patients. We propose the hypothesis that the ERAS pathway could reduce the length of stay (LOS) in hospital for patients undergoing primary THA or TKA.
Methods/Design
This trial is a prospective, open-labelled, multi-centered, randomized controlled trial that will test the superiority of the ERAS pathway in term of LOS in hospital for the patients undergoing primary THA or TKA compared to current non-ERAS clinical practice. A total of 640 patients undergoing primary THA or TKA will be randomly allocated to either ERAS pathway (ERAS group) or conventional care according to individual participating center (non-ERAS group). The primary outcome is the total LOS in hospital; the secondary outcomes include postoperative LOS, all-cause mortality by 30 days after operation, in-hospital complications, early mobilization, postoperative pain control, total in-hospital cost, and readmission rate by 30 days after discharge from the hospital.
Discussion
This trial is designed to evaluate the superiority of the ERAS pathway to conventional non-ERAS clinical practice in reducing the LOS. The results may provide new insight into the clinical applications of the ERAS pathway for THA and TKA.
Trial registration
National Institutes of Health Clinical Trials Registry,
NCT03517098
. Registered on 4 May 2018.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Arthroplasty, Replacement, Hip - adverse effects
/ Arthroplasty, Replacement, Hip - economics
/ Arthroplasty, Replacement, Hip - mortality
/ Arthroplasty, Replacement, Knee - adverse effects
/ Arthroplasty, Replacement, Knee - economics
/ Arthroplasty, Replacement, Knee - mortality
/ China
/ Enhanced recovery after surgery
/ Female
/ Hip replacement arthroplasty
/ Humans
/ Knee replacement arthroplasty
/ Male
/ Medicine
/ Methods
/ Multicenter Studies as Topic
/ Postoperative Complications - etiology
/ R&D
/ Randomized Controlled Trials as Topic
