Asset Details
Do you wish to reserve the book?
Effects of Hypertonic Sodium Lactate on Intracranial Pressure in Patients With Traumatic Brain Injury: A Systematic Review and Meta-analysis on Clinical Trial Studies
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Effects of Hypertonic Sodium Lactate on Intracranial Pressure in Patients With Traumatic Brain Injury: A Systematic Review and Meta-analysis on Clinical Trial Studies
Do you wish to request the book?
Effects of Hypertonic Sodium Lactate on Intracranial Pressure in Patients With Traumatic Brain Injury: A Systematic Review and Meta-analysis on Clinical Trial Studies
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Effects of Hypertonic Sodium Lactate on Intracranial Pressure in Patients With Traumatic Brain Injury: A Systematic Review and Meta-analysis on Clinical Trial Studies
2024
Overview
Introduction: Intracranial pressure (ICP) elevation leading to cerebral edema is a critical condition that should be identified and treated immediately. In this study, we systematically reviewed the articles investigating the role of hypertonic sodium lactate (HSL) in patients with traumatic brain injury (TBI).Methods: PubMed, Scopus, Embase, and Web of Science were searched to find published articles on the effects of HSL on ICP in patients with a TBI until December 2020. Animal studies, case reports, and studies, including patients with liver and renal failure, cardiac dysfunction, or hypovolemic shock, were excluded. The Newcastle-Ottawa scale checklist was used to assess the methodological quality of eligible articles. Information obtained was classified based on the following criteria: demographic data, methods, intervention, and outcomes.Results: Our initial search with the predefined search strategy proceeded with 113 studies. Finally, 7 studies were eligible for systematic review, and 3 of them were eligible for meta-analysis. A random meta-analysis of 3 articles comparing ICP before and after the infusion of HSL showed a reduced ICP following the use of HSL in traumatic brain injuries (P=0.015).Conclusion: Our study demonstrated the undeniable role of HSL in managing increased ICP in patients with brain injury. Nevertheless, conducting more clinical studies to assess the possible side effects of HSL seems crucial.
Publisher
Negah Scientific Publisher
