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Chaotic dynamics underpins the slow oscillation of general anesthesia and nonREM sleep
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Chaotic dynamics underpins the slow oscillation of general anesthesia and nonREM sleep
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Journal Article
Chaotic dynamics underpins the slow oscillation of general anesthesia and nonREM sleep
2012
Overview
Electrical recordings of brain activity show that entry into anesthetic unconsciousness is signposted by the emergence of large, slow oscillations of electrical activity (~1 Hz) that appear very similar to the slow waves observed in natural sleep. Anesthetic effect is modeled as a moderate reduction in inhibitory diffusion, paired with an increase in inhibitory postsynaptic potential. SEE PDF] Conclusion A spontaneous, spatiotemporally chaotic state—generated by nonlinear Turing–Hopf interaction—is the underlying mechanism for the slow oscillation observed in general anesthesia.
Publisher
BioMed Central,Springer Nature B.V,BMC
Subject
