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$BCMA T-Cell Engager Therapy in Patients with Refractory Autoimmune Disease$

BCMA T-Cell Engager Therapy in Patients with Refractory Autoimmune Disease

by Auth, Janina , Munoz, Luis , Wirsching, Andreas , Tur, Carlo , Schett, Georg , Noethling, Danae , Wacker, Jochen , Bozec, Aline , Alivernini, Stefano , Rothe, Tobias , Bucci, Laura , Böltz, Sebastian , Raimondo, Maria Gabriella , Rech, Jürgen , Hagen, Melanie , Bergmann, Christina , D’Agostino, Maria-Antonietta , Eckstein, Markus , Grieshaber-Bouyer, Ricardo , Kihm, Lars

in Allergy / Antibodies / Arthritis / Autoimmune Disease / Autoimmune diseases / Bacterial infections / C-reactive protein / Carbon monoxide / Clinical Medicine / Clinical Medicine General / Critical Care / Critical Care General / Cytokine storm / Dermatology / Dermatology General / Drug dosages / Females / Gastroenterology / Gastroenterology General / Graves disease / Hematology / Immunology / Immunology General / Induction therapy / Lung diseases / Lymphocytes B / Lymphocytes T / Medical diagnosis / Nephrology / Nephrology General / Neurotoxicity / Oncology / Oncology General / Otolaryngology / Otolaryngology General / Outpatient-Based Clinical Medicine / Patients / Pediatrics / Pediatrics General / Pulmonary / Rheumatoid Arthritis / Rheumatology / Rheumatology General / Scleroderma / T-Cells / Tomography / Urinary tract diseases / Urinary tract infections / Urogenital system / Vasculitis

2025

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BCMA T-Cell Engager Therapy in Patients with Refractory Autoimmune Disease

2025

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$BCMA T-Cell Engager Therapy in Patients with Refractory Autoimmune Disease$

BCMA T-Cell Engager Therapy in Patients with Refractory Autoimmune Disease

2025

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$BCMA T-Cell Engager Therapy in Patients with Refractory Autoimmune Disease$

Journal Article

BCMA T-Cell Engager Therapy in Patients with Refractory Autoimmune Disease

Auth, Janina,

Munoz, Luis,

Wirsching, Andreas,

Tur, Carlo,

Schett, Georg,

Noethling, Danae,

Wacker, Jochen,

Bozec, Aline,

Alivernini, Stefano,

Rothe, Tobias,

Bucci, Laura,

Böltz, Sebastian,

Raimondo, Maria Gabriella,

Rech, Jürgen,

Hagen, Melanie,

Bergmann, Christina,

D’Agostino, Maria-Antonietta,

Eckstein, Markus,

Grieshaber-Bouyer, Ricardo,

Kihm, Lars

2025

Overview

Teclistamab, a T-cell engager targeting B-cell maturation antigen, showed promise as a rescue therapy in 10 patients with refractory autoimmune diseases and led to clinical and serologic improvements in most patients.

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Publisher

Massachusetts Medical Society

Subject

/ Autoimmune diseases

/ Bacterial infections

/ C-reactive protein