Journal Article

Biosynthesis of trimetallic nanoparticles and their biological applications: a recent review

Nahool, Ahmed Abdelhay, Dora, Mohamed Soliman, Saied, Ebrahim, Elkady, Fathy M., Attia, Mohamed S., Ali, Mohamed Abdelrahman, Nouh, Mustafa A., Nafea, Mohamed E., Khalifa, Ahmed Nageh, Issa, Nasser Ibrahim, Adel, Albraa, Abdelaziz, Amer Morsy, Hawela, Ahmed Mostafa, Hashem, Amr H., Badr, Bahaa M., Hasib, Abdulrahman, Diab, Mahmoud A., Hamdy, Ziad A., El-Gazzar, Menna M.

2025

Overview

Trimetallic nanoparticles (TMNPs) have emerged as a pivotal area of research due to their unique properties and diverse applications across medicine, agriculture, and environmental sciences. This review provides several novel contributions that distinguish it from existing literature on trimetallic nanoparticles (TMNPs). Firstly, it offers a focused exploration of TMNPs, specifically addressing their unique properties and applications, which have been less examined compared to other multimetallic nanoparticles. This targeted analysis fills a significant gap in current research. Secondly, the review emphasizes innovative biosynthesis methods utilizing microorganisms and plant extracts, positioning these green synthesis approaches as environmentally friendly alternatives to traditional chemical methods. This focus aligns with the increasing demand for sustainable practices in nanotechnology. Furthermore, the review integrates discussions on both medical and agricultural applications of TMNPs, highlighting their multifunctional potential across diverse fields. This comprehensive perspective enhances our understanding of how TMNPs can address various challenges. Additionally, the review explores the synergistic effects among the different metals in TMNPs, providing insights into how these interactions can be harnessed to optimize their properties for specific applications. Such discussions are often overlooked in existing studies. Moreover, this review identifies critical research gaps and challenges within the field, outlining future directions that encourage further investigation and innovation in TMNP development. By doing so, it proactively contributes to advancing the field. Finally, the review advocates for interdisciplinary collaboration among material scientists, biologists, and environmental scientists, emphasizing the importance of diverse expertise in enhancing the research and application of TMNPs.

• Publisher: Springer Berlin Heidelberg,Springer Nature B.V
• Subject: Bacteria - metabolism / Biochemistry / Biological properties / Biomedical and Life Sciences / Biosynthesis / Biotechnology / Cell Biology / Chemical synthesis / Ecology / Environmental science / Humans / Life Sciences / medicine / Metal Nanoparticles - chemistry / Metals / Microbial Ecology / Microbiology / Microorganisms / Nanoparticles / Nanotechnology / Nanotechnology - methods / Plant extracts / Plant Extracts - chemistry / Plant Extracts - metabolism / Review / Scientists / Sustainable practices / Synergistic effect