Journal Article

Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes

Perkovic, Vlado, Tuttle, Katherine R., Pratley, Richard, Lausvig, Nanna Leonora, Baeres, Florian M.M., Mahaffey, Kenneth W., Rossing, Peter, Bakris, George, Bosch-Traberg, Heidrun, Idorn, Thomas, Mann, Johannes F.E.

2024

Overview

In patients with type 2 diabetes and chronic kidney disease, weekly semaglutide significantly reduced risks of major kidney events, cardiovascular events, and death from any cause while slowing loss of kidney function.

• Publisher: Massachusetts Medical Society
• Subject: Aged / Albumin / Antidiabetics / Cardiovascular diseases / Cardiovascular Diseases - etiology / Cardiovascular Diseases - mortality / Cardiovascular Diseases - prevention & control / Chronic Kidney Disease / Clinical Medicine / Clinical Medicine General / Creatinine / Death / Diabetes / Diabetes mellitus (non-insulin dependent) / Diabetes Mellitus, Type 2 - complications / Diabetes Mellitus, Type 2 - drug therapy / Diabetic Nephropathies - etiology / Diabetic Nephropathies - mortality / Dialysis / Double-Blind Method / Endocrinology / Epidermal growth factor receptors / Female / Glomerular filtration rate / Glomerular Filtration Rate - drug effects / Glucagon-Like Peptide-1 Receptor Agonists - administration & dosage / Glucagon-Like Peptide-1 Receptor Agonists - adverse effects / Glucagon-Like Peptide-1 Receptor Agonists - therapeutic use / Glucagon-Like Peptides - administration & dosage / Glucagon-Like Peptides - adverse effects / Glucagon-Like Peptides - pharmacology / Glucagon-Like Peptides - therapeutic use / Humans / Hypoglycemic Agents - administration & dosage / Hypoglycemic Agents - adverse effects / Hypoglycemic Agents - therapeutic use / Hypothesis testing / Injections, Subcutaneous / Kidney diseases / Kidney transplantation / Laboratories / Male / Middle Aged / Nephrology / Placebos / Renal failure / Renal Insufficiency, Chronic - etiology / Renal Insufficiency, Chronic - mortality